- ►nih.gov DJ Drucker - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The gastrointestinal tract has a crucial role in the control of energy
homeostasis through its role in the digestion, absorption, and assimilation of
ingested nutrients. Furthermore, signals from the gastrointestinal tract ... Cited by 85 - Related articles - BL Direct - All 11 versions
- ►tufts.edu [PDF] LL Baggio, DJ Drucker, 2006 - Annual Reviews Type 2 diabetes is characterized by hyperglycemia resulting from insulin
resistance in the setting of inadequate β-cell compensation. Currently
available therapeutic agents lower blood glucose through multiple ... Cited by 77 - Related articles - BL Direct - All 10 versions
- ►alphamedpress.org M Mimeault, SK Batra - Stem Cells, 2006 - AlphaMed Press In this study, we report on recent advances on the functions of embryonic,
fetal, and adult stem cell progenitors for tissue regeneration and cancer
therapies. We describe new procedures for derivation and maturation of ... Cited by 77 - Related articles - BL Direct - All 9 versions
PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ... Cited by 41 - Related articles - BL Direct - All 3 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative
lack of insulin-producing β cells, respectively. Reconstitution of a functional
β-cell mass by cell therapy – using organ donor islets of Langerhans – ... Cited by 27 - Related articles - BL Direct - All 6 versions
BA Menge, A Tannapfel, O Belyaev, R Drescher … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Protocol 1: fasting glucose concentrations increased significantly
after the 50% pancreatectomy (P = 0.01), but the fractional β-cell area of the
pancreas remained unchanged (P = 0.11). β-Cell proliferation, the overall ... Cited by 23 - Related articles - BL Direct - All 5 versions
JJ Meier, AE Butler, R Galasso, RA Rizza, PC … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Type 1 and type 2 diabetes are charac- terised by a
beta cell deficit. Islet hyperplasia has been described in patients with
Zollinger–Ellison syndrome secondary to gastrin-producing tumours ... Cited by 21 - Related articles - BL Direct - All 5 versions
- ►endojournals.org MY Donath, J Storling, LA Berchtold, N … - Endocrine Reviews, 2008 - Endocrine Soc The tale of cytokines and the β-cell is a long story, starting with in vitro
discovery in 1984, evolving via descriptive and phenomenological studies to
detailed mapping of the signalling pathways, gene- and protein expression ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►nih.gov D Bresson, M Von Herrath - Autoimmunity reviews, 2007 - Elsevier Every year, thirty thousand people worldwide are diagnosed with type 1 diabetes
mellitus (T1DM). T1DM, also called autoimmune diabetes, is a multifactorial
disease affecting predisposed individuals and involving genetic ... Cited by 20 - Related articles - All 3 versions
- ►nih.gov H Mziaut, S Kersting, KP Knoch, WH Fan, M … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Changes in metabolic demands dynamically regulate the total mass of adult
pancreatic β-cells to adjust insulin secretion and preserve glucose
homeostasis. Glucose itself is a major regulator of β-cell proliferation ... Cited by 15 - Related articles - BL Direct - All 7 versions
