WW Song, A Ergul - Cardiovascular Diabetology, 2006 - cardiab.com Hyperglycemia-induced changes in vascular wall structure contribute to the pathogenesis of
diabetic microvascular and macrovascular complications. Matrix metalloproteinases (MMP),
a family of proteolytic enzymes that degrade extracellular matrix (ECM) proteins, are ... Cited by 15 - Related articles - Cached - All 10 versions
- ►diabetesjournals.org V Novak, D Last, DC Alsop, AM Abduljalil, K Hu, L … - Diabetes care, 2006 - Am Diabetes Assoc OBJECTIVE—Diabetes increases the risk for cerebromicrovascular disease, possibly through
its effects on blood flow regulation. The aim of this study was to assess the effects of type 2 diabetes
on blood flow velocities (BFVs) in the middle cerebral arteries and to determine the ... Cited by 12 - Related articles - BL Direct - All 6 versions
- ►iovs.org ED Gilmore, C Hudson, RK Nrusimhadevara, PT … - … Ophthalmology & Visual …, 2007 - ARVO RESULTS. Changes in blood velocity and wall shear rate (WSR) were significantly less in groups
3 and 4 (P < 0.0001 and P = 0.0002, respectively) than in groups 1 and 2. Change in blood flow
was significantly less in group 4 (P < 0.004) than in groups 1 and 2. The change in ... Cited by 9 - Related articles - BL Direct - All 3 versions
A Ergul, MM Elgebaly, ML Middlemore, W Li, H … - BMC neurology, 2007 - biomedcentral.com Interruption of flow through of cerebral blood vessels results in acute ischemic stroke. Subsequent
breakdown of the blood brain barrier increases cerebral injury by the development of vasogenic
edema and secondary hemorrhage known as hemorrhagic transformation (HT). Diabetes ... Cited by 9 - Related articles - Cached - All 6 versions
- ►diabetesjournals.org K Sachidanandam, V Portik-Dobos, AK Harris, JR … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Vascular remodeling, characterized by extracellular matrix deposition and increased
media-to-lumen (M/l) ratio, contributes to the development of microvascular complications in
diabetes. Matrix metalloproteinases (MMPs) play an important role in the regulation of ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►physiology.org AK Harris, MM Elgebaly, W Li, K … - American Journal of …, 2008 - Am Physiological Soc Diabetes increases the risk of stroke and contributes to poor clinical outcomes in this patient
population. Myogenic tone of the cerebral vasculature, including basilar arteries, plays a key
role in controlling cerebral blood flow. Increased myogenic tone is ameliorated with ET ... Cited by 7 - Related articles - BL Direct - All 4 versions
MM Elgebaly, A Kelly, AK Harris, H Elewa, V … - Canadian Journal of …, 2008 - ingentaconnect.com Abstract: Insulin resistance involves decreased phosphorylation of insulin receptor substrate
(IRS) proteins and (or) Akt. In the vasculature, modulated Akt phosphorylation may cause impaired
vasorelaxation via decreased eNOS activation. Diet-induced insulin resistance enhances ... Cited by 5 - Related articles - All 6 versions
A Ergul, D Jupin, MH Johnson, LM Prisant - J Clin Hypertens, 2006 - interscience.wiley.com Endothelin-1 stimulates collagen synthesis and is increased in hypertension, but its effect on
collagen degradation remains unknown. The current study tested the hypothesis that elevated
endothelin-1 levels are associated with decreased collagenase activity, markers of ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►physiology.org … , MM Elgebaly, AK Harris, JR Hutchinson, … - American Journal of …, 2008 - Am Physiological Soc Vascular dysfunction, which presents either as an increased response to vasoconstrictors or
an impaired relaxation to dilator agents, results in worsened cardiovascular outcomes in
diabetes. We have established that the mesenteric circulation in Type 2 diabetes is ... Cited by 4 - Related articles - All 3 versions
ME Ivey, N Osman, PJ Little - Atherosclerosis, 2008 - Elsevier Atherosclerosis is the primary ischaemic vascular condition underlying a majority of cardiovascular
disease related deaths. Endothelin-1 is a vasoactive peptide agent upregulated in atherosclerosis
and in conjunction with its G protein-coupled receptors exerts diverse actions on all cells ... Cited by 5 - Related articles - All 23 versions
