DM Lehman, KJ Hunt, RJ Leach, J Hamlington, R Arya, … - Diabetes, 2007 - Am Diabetes Assoc TCF7L2 acts as both a repressor and transactivator of genes, as directed by the Wnt signaling
pathway. Recently, several highly correlated sequence variants located within a haplotype block
of the TCF7L2 gene were observed to associate with type 2 diabetes in three Caucasian ... Cited by 49 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains
differ in the response of their critical physiological functions, such as insulin sensitivity, ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►kuleuven.be [PDF] CC Elbers, NC Onland-Moret, L Franke, AG Niehoff, … - Trends in Endocrinology & …, 2007 - Elsevier Worldwide, the incidence of type 2 diabetes is rising rapidly, mainly because of the increase
in the incidence of obesity, which is an important risk factor for this condition. Both obesity and
type 2 diabetes are complex genetic traits but they also share some nongenetic risk ... Cited by 18 - Related articles - All 7 versions
- ►oxfordjournals.org R Arya, E Demerath, CP Jenkinson, HHH … - Human Molecular …, 2006 - Oxford Univ Press Low birth weight is an important cause of infant mortality and morbidity worldwide. Birth weight
has been shown to be inversely correlated with adult complex diseases such as obesity,
type-2 diabetes and cardiovascular disease. However, little is known about the genetic ... Cited by 12 - Related articles - BL Direct - All 8 versions
DM Lehman, DK Richardson, CP Jenkinson, KJ Hunt, … - Diabetes, 2007 - Am Diabetes Assoc Common and rare variants of the hepatocyte nuclear factor 4α (HNF4A) gene have been associated
with type 2 diabetes and related traits in several populations suggesting the involvement of this
transcription factor in diabetes pathogenesis. Single nucleotide polymorphisms (SNPs) ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►shouxi.net S Puppala, R Arya, F Thameem, NH Arar, K Bhandari, … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—GFR (N = 453) was estimated using the recently recalculated
Cockcroft-Gault (GFR-CGc) and the simplified Modification of Diet in Renal Disease
(GFR-4VMDRD) formulae. Both estimates of GFR exhibited significant heritabilities, but ... Cited by 9 - Related articles - BL Direct - All 4 versions
D Warren, M Stern, R Duggirala, T Dyer, L … - … : Asymmetries of Body, …, 2006 - ingentaconnect.com Page 1. Heritability and linkage analysis of hand, foot, and eye preference in Mexican Americans
Diane M. Warren Southwest Foundation for Biomedical Research, San Antonio, TX, USA Michael
Stern University of Texas Health Science Center, San Antonio, TX, USA ... Cited by 4 - Related articles - BL Direct - All 3 versions
DM Lehman, J Hamlington, KJ Hunt, RJ … - Diabetes/Metabolism … - interscience.wiley.com The human 3-adrenergic receptor gene (ADRB3) has been investigated as a candidate gene
for diabetes-related traits in many studies. However, the results have been inconsistent so it is
unclear whether variation in ADRB3 is a risk factor for type 2 diabetes. We have identified ... Cited by 3 - Related articles - BL Direct - All 4 versions
DK Coletta, J Schneider, SL Hu, TD Dyer, S Puppala, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—After adjusting for the significant effects of sex and BMI, heritability for plasma triglycerides
was estimated as 46 ± 7% (P < 0.0001). Multipoint linkage analysis yielded the strongest evidence
for linkage of plasma triglycerides near marker D12S391 on chromosome 12p (logarithm ... Cited by 2 - Related articles - All 3 versions
