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Scholar Results 1 - 10 of about 17 citing Lam: Transgenic mouse overexpressing syntaxin-1A as a diabetes model. (0.25 sec) 

Imaging analysis reveals mechanistic differences between first-and second-phase insulin …

- rupress.org
M Ohara-Imaizumi, T Fujiwara, Y Nakamichi, … - Journal of Cell Biology, 2007 - jcb.rupress.org
The mechanism of glucose-induced biphasic insulin release is unknown. We used
total internal reflection fluorescence (TIRF) imaging analysis to reveal the
process of first- and second-phase insulin exocytosis in pancreatic ß ...
Cited by 30 - Related articles - BL Direct - All 7 versions

Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance

- diabetesjournals.org
EP Kwan, L Xie, L Sheu, CJ Nolan, M Prentki, … - Diabetes, 2006 - Am Diabetes Assoc
Munc13-1 is a diacylglycerol (DAG) receptor that is essential for synaptic
vesicle priming. We recently showed that Munc13-1 is expressed in rodent and
human islet β-cells and that its levels are reduced in islets of type 2 ...
Cited by 21 - Related articles - All 5 versions

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion …


KM Ramsey, KF Mills, A Satoh, S Imai - Aging cell, 2008 - pubmedcentral.nih.gov
Cited by 19 - Related articles - BL Direct - All 4 versions

Domain requirement for the membrane trafficking and targeting of syntaxin 1A

- jbc.org
X Yang, P Xu, Y Xiao, X Xiong, T Xu - Journal of Biological Chemistry, 2006 - ASBMB
Syntaxin plays a key role in intracellular membrane fusion in eukaryotic cells.
The function of syntaxin relies on its proper trafficking to and targeting at
the target membrane. The mechanisms underlying the trafficking and ...
Cited by 16 - Related articles - BL Direct - All 9 versions

Are the available experimental models of type 2 diabetes appropriate for a gender …


F Franconi, G Seghieri, S Canu, E Straface, I … - Pharmacological Research, 2008 - Elsevier
Several experimental models have so far been developed to improve our knowledge
of the pathogenetic mechanisms of type 2 diabetes mellitus (T2D), to determine
the possible pharmacological targets of this disease and to better evaluate ...
Cited by 7 - Related articles - All 3 versions

Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and …


J Souza-Menezes, M Morales, D Tukaye, S … - Cell Physiol Biochem, 2007 - content.karger.com
Page 1. 455 Original Paper Cell Physiol Biochem 2007;20:455-464 Accepted: March
29, 2007 Cellular Physiology and Biochemistry Copyright ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Dynamin is functionally coupled to insulin granule exocytosis

- jbc.org
L Min, YM Leung, A Tomas, RT Watson, HY … - Journal of Biological Chemistry, 2007 - ASBMB
The insulin granule integral membrane protein marker phogrin-green fluorescent
protein was co-localized with insulin in Min6B1 -cell secretory granules but did
not undergo plasma membrane translocation following glucose stimulation. ...
Cited by 5 - Related articles - All 5 versions

The Actions of a Novel Potent Islet β-Cell–Specific ATP-Sensitive K+ Channel Opener Can …

- diabetesjournals.org
B Ng, Y Kang, CL Elias, Y He, H Xie, JB … - Diabetes, 2007 - Am Diabetes Assoc
Islet β-cell–specific ATP-sensitive K + (K ATP ) channel openers thiadiazine
dioxides induce islet rest to improve insulin secretion, but their molecular
basis of action remains unclear. We reported that syntaxin-1A binds ...
Cited by 2 - Related articles - BL Direct - All 4 versions

The actions of a novel potent islet beta-cell specific KATP channel opener can be modulated …

- diabetesjournals.org [PDF] 
B Ng, Y Kang, CL Elias, Y He, H Xie, JB … - Diabetes, 2007 - Am Diabetes Assoc
Page 1. The actions of a novel potent islet beta-cell specific KATP channel opener
can be modulated by syntaxin-1A acting on sulfonylurea receptor 1 ...
Cited by 2 - Related articles - All 2 versions

Interaction of Munc18 and Syntaxin in the regulation of insulin secretion


Y Dong, Q Wan, X Yang, L Bai, P Xu - Biochemical and Biophysical Research …, 2007 - Elsevier
Syntaxin1A and Munc18-1 play essential roles in exocytosis. However, the
molecular mechanism and the functional roles of their interaction in insulin
secretion remain to be explored. Using membrane capacitance measurement, we ...
Cited by 3 - Related articles - All 6 versions


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