- ►diabetesjournals.org C Pihoker, LK Gilliam, CS Hampe, Å … - Diabetes, 2005 - Am Diabetes Assoc Islet cell autoantibodies are strongly associated with the development of type 1
diabetes. The appearance of autoantibodies to one or several of the
autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis ... Cited by 53 - Related articles - BL Direct - All 6 versions
DJ Smyth, V Plagnol, NM Walker, JD Cooper … - The New England Journal of Medicine, 2008 - nejm.highwire.org From the Juvenile Diabetes Research Foundation–Wellcome Trust Diabetes and
Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for
Medical Research, University of Cambridge, Addenbrooke's Hospital, ... Cited by 44 - Related articles - All 5 versions
CH Wasserfall, MA Atkinson - Autoimmunity Reviews, 2006 - Elsevier Type 1 diabetes results from the autoimmune destruction of the insulin producing
pancreatic β-cells. For years, the notion that T-lymphocytes played a crucial
role in the disorder's formation was considered such sound dogma, that ... Cited by 31 - Related articles - All 2 versions
JF Ludvigsson, J Ludvigsson, A Ekbom, SM … - Diabetes Care, 2006 - Am Diabetes Assoc OBJECTIVE—Earlier studies suggest that children with type 1 diabetes are more
likely to have a subsequent diagnosis of celiac disease. However, research is
sparse on the risk of subsequent type 1 diabetes in individuals with celiac ... Cited by 28 - Related articles - BL Direct - All 8 versions
R Bailey, JD Cooper, L Zeitels, DJ Smyth, … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Epidemiological studies have linked vitamin D deficiency with the
susceptibility to type 1 diabetes. Higher levels of the active metabolite
1α,25-dihydroxyvitamin D (1α,25(OH) 2 D) could protect from immune ... Cited by 27 - Related articles - BL Direct - All 9 versions
- ►oxfordjournals.org G Lettre, JD Rioux - Human Molecular Genetics, 2008 - Oxford Univ Press Autoimmune diseases occur when an individual's own immune system attacks and
destroys his or her healthy cells and tissues. Although it is clear that
environmental stimuli can predispose someone to develop autoimmune ... Cited by 27 - Related articles - All 4 versions
M Knip, H Siljander - Autoimmunity Reviews, 2008 - Elsevier Type 1 diabetes (T1D) is perceived as a chronic immune-mediated disease with a
subclinical prodromal period characterized by selective loss of
insulin-producing β-cells in the pancreatic islets in genetically ... Cited by 23 - Related articles - All 2 versions
- ►nih.gov JMM Howson, DB Dunger, S Nutland, H … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis HLA haplotypes DRB1*03_DQB1*02 and DRB1*04_DQB1*0302,
and allelic variation of the T cell regulatory gene cytotoxic
T-lymphocyte-associated antigen-4 (CTLA4) and of the T cell activation gene ... Cited by 23 - Related articles - BL Direct - All 8 versions
H Peng, W Hagopian - Reviews in Endocrine & Metabolic Disorders, 2006 - Springer Abstract Environmental factors appear to play an important role in the
pathogenesis of childhood-onset type 1 diabetes (T1D). The most important
factors are thought to be infectious, dietary, perinatal, and psychosocial. ... Cited by 22 - Related articles - BL Direct - All 3 versions
M Mäkelä, O Vaarala, R Hermann, K Salminen, … - Journal of Autoimmunity, 2006 - Elsevier Enteral virus infections may trigger the development of β-cell-specific
autoimmunity by interacting with the gut-associated lymphoid system. We analyzed
the effect of three different virus infections on immunization to dietary ... Cited by 17 - Related articles - All 5 versions
