TP Di Lorenzo, M Peakman, BO … - Clinical and Experimental …, 2007 - pubmedcentral.nih.gov T cell epitopes represent the molecular code words through which the adaptive immune system
communicates. In the context of a T cell-mediated autoimmune disease such as type 1 diabetes, CD4
and CD8 T cell recognition of islet ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org E Martinuzzi, G Novelli, M Scotto, P Blancou, JM Bach, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—CD8 + T-cell reactivities were less frequent at follow-up, as 28.6% of responses tested
positive at type 1 diabetes diagnosis vs. 13.2% after a median of 11 months (P = 0.003). While GAD
and IA-2 autoantibody (aAb) titers ... Cited by 12 - Related articles - BL Direct - All 9 versions
- ►endojournals.org A Kubosaki, S Nakamura, A Clark, JF Morris, AL … - Endocrinology, 2006 - Endocrine Soc Female infertility is a worldwide problem affecting 10–15% of the population. The cause of the
infertility in many cases is not known. In the present report, we demonstrate that alterations in
two transmembrane structural ... Cited by 10 - Related articles - BL Direct - All 5 versions
WJ Hendriks, A Elson, S Harroch, AW Stoker - FEBS journal, 2008 - assets0.pubget.com Research on how oncoviruses transform mammalian cells has led to the firm establishment of the
tyrosine- specific phosphorylation of cellular proteins as a key signalling mechanism to evoke
essential cell decisions, for ... Cited by 10 - Related articles - View as HTML - BL Direct - All 8 versions
- ►diabetesjournals.org S Salinari, A Bertuzzi, S Asnaghi, C Guidone, M … - Diabetes Care, 2009 - Am Diabetes Assoc RESULTS—The first phase of insulin secretion after the IVGTT was fully normalized after the
operation. The disposition index from OGTT data was increased about 10-fold and became similar to
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- ►endocrinology-journals.org JC Henquin, M Nenquin, A Szollosi, A … - Journal of …, 2008 - Soc Endocrinology Islet antigen-2 (IA-2 or ICA 512) and IA-2β (or phogrin) are major autoantigens in type 1 diabetes.
They are located in dense core secretory vesicles including insulin granules, but their role in
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- ►diabetesjournals.org S Torii, N Saito, A Kawano, N Hou, K Ueki, RN Kulkarni … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Adenoviral expression of shPhogrin efficiently decreased its endogenous expression in
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SM Kim, A Power, TM Brown, CM Constance, SL Coon, … - sne.nichd.nih.gov ABSTRACT Targeted deletion of IA-2 and IA-2ß, major autoantigens in type 1 diabetes and transmem-
brane secretory vesicle proteins, results in impaired secretion of hormones and neurotransmitters.
In the present study, we evaluated ... Related articles - View as HTML
T Cai, H Hirai, T Fukushige, P Yu, G Zhang, AL … - PLoS …, 2009 - pubmedcentral.nih.gov It is generally accepted that neuroendocrine cells regulate dense core vesicle (DCV) biogenesis and
cargo packaging in response to secretory demands, although the molecular mechanisms of this process
are poorly understood. One factor ... Related articles - All 5 versions
SM Kim, A Power, TM Brown, CM Constance, SL Coon, … - The FASEB Journal, 2009 - FASEB Targeted deletion of IA-2 and IA-2β, major autoantigens in type 1 diabetes and transmembrane
secretory vesicle proteins, results in impaired secretion of hormones and neurotransmitters. In the
present study, we evaluated the ... Related articles - All 3 versions
