- ►pnas.org JM Wenzlau, K Juhl, L Yu, O Moua, SA … - Proceedings of the …, 2007 - National Acad Sciences Type 1 diabetes (T1D) results from progressive loss of pancreatic islet mass through autoimmunity
targeted at a diverse, yet limited, series of molecules that are expressed in the pancreatic β
cell. Identification of these molecular targets provides insight into the pathogenic process, ... Cited by 91 - Related articles - BL Direct - All 6 versions
M Nakamura, H Kondo, T Mori, A Komori, M … - Hepatology, 2007 - interscience.wiley.com The predictive role of antinuclear antibodies (ANAs) remains elusive in the long-term outcome
of primary biliary cirrhosis (PBC). The progression of PBC was evaluated in association with
ANAs using stepwise Cox proportional hazard regression and an unconditional stepwise ... Cited by 57 - Related articles - BL Direct - All 3 versions
KN Verpoort, CM Jol-Van Der Zijde, EAM … - Arthritis Care & … - interscience.wiley.com IgA, IgM, and IgG subclasses of anti-CCP were measured by enzyme-linked immunosorbent
assay in serum samples that were obtained from IgG anti-CCP antibody-positive patients with
UA (n = 110) and IgG anti-CCP antibody-positive patients with RA (n = 152) early after the ... Cited by 38 - Related articles - BL Direct - All 3 versions
A Molven, M Ringdal, AM Nordbø, H Ræder, J Støy, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Among the MODY patients, we identified the INS mutation c.137G>A (R46Q) in a
proband, his diabetic father, and a paternal aunt. They were diagnosed with diabetes at 20,
18, and 17 years of age, respectively, and are treated with small doses of insulin or diet ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►cell.com D Kabelitz, EK Geissler, B Soria, IS Schroeder, F … - Trends in Immunology, 2008 - Elsevier Type 1 diabetes (T1D) is an autoimmune disease that results from the destruction of insulin-producing
pancreatic islet cells owing to the aggressive effector function of autoreactive T cells. In addition
to lifetime supply of exogenous insulin, whole-pancreas or islet transplantation is ... Cited by 10 - Related articles - All 4 versions
P Pirot, AK Cardozo, DL Eizirik - Arquivos Brasileiros de Endocrinologia & …, 2008 - SciELO Brasil Type 1 diabetes mellitus (T1D) is characterized by severe insulin deficiency resulting from chronic
and progressive destruction of pancreatic beta-cells by the immune system. The triggering of
autoimmunity against the beta-cells is probably caused by environmental agent(s) acting ... Cited by 10 - Related articles - Cached - All 4 versions
TR Hall, JW Thomas, CJ Padoa, C Torn, M … - Clinical and …, 2006 - pubmedcentral.nih.gov Autoantibodies to insulin (IAA) are one of the first markers of the autoimmune process leading
to type 1 diabetes (T1D). While other autoantibodies in T1D have been studied extensively, relatively
little is known about IAA and their binding specificities, especially after insulin treatment is ... Cited by 5 - Related articles - BL Direct - All 6 versions
JM Wenzlau, O Moua, SA Sarkar, L Yu, M Rewers, GS … - System, 1927 - interscience.wiley.com Type 1A diabetes (T1D) results from autoimmunity targeted at a limited number of molecules
that are expressed in the pancreatic β cell. Putative novel autoantigen candidates were identified
from microarray expression profiling of human and rodent islet cells. The highest ranking ... Cited by 6 - Related articles - All 5 versions
JH Shin, M Janer, B McNeney, S Blay, K Deutsch, CB … - Genes and immunity, 2007 - nature.com In a large case-control study of Swedish incident type I diabetes patients and controls, 0–34 years
of age, we tested the hypothesis that the GIMAP5 gene, a key genetic factor for lymphopenia
in spontaneous BioBreeding rat diabetes, is associated with type I diabetes; with islet ... Cited by 5 - Related articles - BL Direct - All 4 versions
R Uibo, A Lernmark - Immunopathogenesis of Type 1 Diabetes …, 2008 - books.google.com GAD65 Autoimmunity—Clinical Studies O j. Raivo Uibo* and Ake Lernmark Contents 1. Introduction
40 1.1. From 64K to GAD65 (1981-1991) 41 1.2. GAD65 and GAD67 structure and function 43
2. GAD65 Autoimmunity in T1D 48 2.1. Cellular GAD65 immunity in T1D 48 2.2. Humoral ... Cited by 2 - Related articles - All 2 versions
