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Scholar Results 1 - 10 of about 83 citing Kukidome: Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial.... (0.08 sec) 

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional …


J St-Pierre, S Drori, M Uldry, JM Silvaggi, … - Cell, 2006 - Elsevier
PPARγ coactivator 1α (PGC-1α) is a potent stimulator of mitochondrial
biogenesis and respiration. Since the mitochondrial electron transport chain is
the main producer of reactive oxygen species (ROS) in most cells, we ...
Cited by 218 - Related articles - All 14 versions

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of …

- nih.gov
S Jäger, C Handschin, J St-Pierre, BM … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Activation of AMP-activated kinase (AMPK) in skeletal muscle increases glucose
uptake, fatty acid oxidation, and mitochondrial biogenesis by increasing gene
expression in these pathways. However, the transcriptional components that ...
Cited by 126 - Related articles - BL Direct - All 9 versions

Resveratrol stimulates AMP kinase activity in neurons

- nih.gov
B Dasgupta, J Milbrandt - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Resveratrol is a polyphenol produced by plants that has multiple beneficial
activities similar to those associated with caloric restriction (CR), such as
increased life span and delay in the onset of diseases associated with ...
Cited by 89 - Related articles - BL Direct - All 8 versions

Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of …

- ahajournals.org
L Tao, E Gao, X Jiao, Y Yuan, S Li, TA … - Circulation, 2007 - Am Heart Assoc
Methods and Results— Adiponectin –/– or wild-type mice were subjected to
30 minutes of myocardial ischemia followed by 3 hours or 24 hours (infarct size
and cardiac function) of reperfusion. Myocardial infarct size and ...
Cited by 66 - Related articles - All 7 versions

Mitochondrial-nuclear communications

- coecxs.org [PDF] 
MT Ryan, NJ Hoogenraad, 2007 - Annual Reviews
Abstract Mitochondria cannot be made de novo but replicate by a mechanism of
recruitment of new proteins, which are added to preexisting subcompartments.
Although mitochondria have their own DNA, more than 98% of the total ...
Cited by 62 - Related articles - BL Direct - All 6 versions

Role of adiponectin in human skeletal muscle bioenergetics

- nih.gov
AE Civitarese, B Ukropcova, S Carling, M … - Cell metabolism, 2006 - Elsevier
Insulin resistance is associated with impaired skeletal muscle oxidation
capacity and reduced mitochondrial number and function. Here, we report that
adiponectin signaling regulates mitochondrial bioenergetics in skeletal ...
Cited by 55 - Related articles - All 15 versions

Adiponectin Suppression of High-Glucose–Induced Reactive Oxygen Species in Vascular …

- diabetesjournals.org
R Ouedraogo, X Wu, SQ Xu, L Fuchsel, H … - Diabetes, 2006 - Am Diabetes Assoc
Adiponectin is an abundant adipocyte-derived plasma protein with
antiatherosclerotic effects. Vascular signal transduction by adiponectin is
poorly understood and may involve 5′-AMP–activated protein kinase ...
Cited by 56 - Related articles - BL Direct - All 6 versions

Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its …


T Nishikawa, E Araki - Antioxidants & Redox Signaling, 2007 - liebertonline.com
T HE MITOCHONDRION is believed to be an organelle derived from a genetic
component(s) of microorganisms, and thus its replication, transcription, and
translation system has been developed on its own basis, although several ...
Cited by 50 - Related articles - BL Direct - All 4 versions

The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences

- clinchem.org
S de Ferranti, D Mozaffarian - Clinical chemistry, 2008 - Am Assoc Clin Chem
Content: In this report we review adipocyte metabolism and function in the
context of energy imbalance and postprandial nutrient excess, including
adipocyte hypertrophy and hyperplasia, adipocyte dysfunction, and other ...
Cited by 48 - Related articles - BL Direct - All 5 versions

Role of mitochondrial dysfunction in insulin resistance

- ahajournals.org
J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc
Insulin resistance is characteristic of obesity, type 2 diabetes, and components
of the cardiometabolic syndrome, including hypertension and dyslipidemia, that
collectively contribute to a substantial risk for cardiovascular disease. ...
Cited by 49 - Related articles - All 6 versions


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