J St-Pierre, S Drori, M Uldry, JM Silvaggi, … - Cell, 2006 - Elsevier PPARγ coactivator 1α (PGC-1α) is a potent stimulator of mitochondrial
biogenesis and respiration. Since the mitochondrial electron transport chain is
the main producer of reactive oxygen species (ROS) in most cells, we ... Cited by 218 - Related articles - All 14 versions
- ►nih.gov S Jäger, C Handschin, J St-Pierre, BM … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Activation of AMP-activated kinase (AMPK) in skeletal muscle increases glucose
uptake, fatty acid oxidation, and mitochondrial biogenesis by increasing gene
expression in these pathways. However, the transcriptional components that ... Cited by 126 - Related articles - BL Direct - All 9 versions
- ►nih.gov B Dasgupta, J Milbrandt - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Resveratrol is a polyphenol produced by plants that has multiple beneficial
activities similar to those associated with caloric restriction (CR), such as
increased life span and delay in the onset of diseases associated with ... Cited by 89 - Related articles - BL Direct - All 8 versions
- ►ahajournals.org L Tao, E Gao, X Jiao, Y Yuan, S Li, TA … - Circulation, 2007 - Am Heart Assoc Methods and Results— Adiponectin –/– or wild-type mice were subjected to
30 minutes of myocardial ischemia followed by 3 hours or 24 hours (infarct size
and cardiac function) of reperfusion. Myocardial infarct size and ... Cited by 66 - Related articles - All 7 versions
- ►coecxs.org [PDF] MT Ryan, NJ Hoogenraad, 2007 - Annual Reviews Abstract Mitochondria cannot be made de novo but replicate by a mechanism of
recruitment of new proteins, which are added to preexisting subcompartments.
Although mitochondria have their own DNA, more than 98% of the total ... Cited by 62 - Related articles - BL Direct - All 6 versions
- ►nih.gov AE Civitarese, B Ukropcova, S Carling, M … - Cell metabolism, 2006 - Elsevier Insulin resistance is associated with impaired skeletal muscle oxidation
capacity and reduced mitochondrial number and function. Here, we report that
adiponectin signaling regulates mitochondrial bioenergetics in skeletal ... Cited by 55 - Related articles - All 15 versions
- ►diabetesjournals.org R Ouedraogo, X Wu, SQ Xu, L Fuchsel, H … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin is an abundant adipocyte-derived plasma protein with
antiatherosclerotic effects. Vascular signal transduction by adiponectin is
poorly understood and may involve 5′-AMP–activated protein kinase ... Cited by 56 - Related articles - BL Direct - All 6 versions
T Nishikawa, E Araki - Antioxidants & Redox Signaling, 2007 - liebertonline.com T HE MITOCHONDRION is believed to be an organelle derived from a genetic
component(s) of microorganisms, and thus its replication, transcription, and
translation system has been developed on its own basis, although several ... Cited by 50 - Related articles - BL Direct - All 4 versions
- ►clinchem.org S de Ferranti, D Mozaffarian - Clinical chemistry, 2008 - Am Assoc Clin Chem Content: In this report we review adipocyte metabolism and function in the
context of energy imbalance and postprandial nutrient excess, including
adipocyte hypertrophy and hyperplasia, adipocyte dysfunction, and other ... Cited by 48 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc Insulin resistance is characteristic of obesity, type 2 diabetes, and components
of the cardiometabolic syndrome, including hypertension and dyslipidemia, that
collectively contribute to a substantial risk for cardiovascular disease. ... Cited by 49 - Related articles - All 6 versions