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Scholar Results 1 - 10 of about 77 citing Otonkoski: Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron.... (0.09 sec) 

Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa …


OT Hardy, M Hernandez-Pampaloni, JR Saffer, M … - The Journal of Pediatrics, 2007 - Elsevier
The diagnosis of focal or diffuse hyperinsulinism was correct in 23 of the 24 cases (96%) and
equivocal in 1 case. [ 18 F]-DOPA PET identified focal areas of high uptake of radiopharmaceutical
in 11 patients. Pathology results confirmed that all 11 had focal adenomatosis, and the ...
Cited by 45 - Related articles - All 14 versions

Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) positron emission tomography …

- endojournals.org
S Kauhanen, M Seppanen, H Minn, R … - Journal of Clinical …, 2007 - Endocrine Soc
Context and Objective: Fluorine-18-L-dihydroxyphenylalanine ( 18 F-DOPA) positron emission
tomography (PET) is a promising method in localizing neuroendocrine tumors. Recently, it has
been shown to differentiate focal forms of congenital hyperinsulinism of infancy. The ...
Cited by 38 - Related articles - BL Direct - All 3 versions

Congenital hyperinsulinism: pancreatic [18F] fluoro-L-dihydroxyphenylalanine ( …

- endojournals.org
P de Lonlay, A Simon-Carre, MJ Ribeiro, N … - Journal of Clinical …, 2006 - Endocrine Soc
Results: Immunohistochemical detection of DOPA decarboxylase showed diffuse staining of
Langerhans islets in the whole pancreas in all diffuse cases, in contrast with dense focal staining
in all focal cases. Staining of Langerhans islets outside the focal lesion was diffusely but ...
Cited by 29 - Related articles - BL Direct - All 3 versions

Mechanisms of disease: advances in diagnosis and treatment of hyperinsulinism in …


DD De León, CA Stanley - Nature Clinical Practice Endocrinology & …, 2007 - nature.com
Diva D De León is an Assistant Professor of Pediatrics at the University of Pennsylvania,
Philadelphia, PA, USA, and an Attending Physician in the Division of Endocrinology, The Children's
Hospital of Philadelphia. Her research interest is on disorders of carbohydrate ...
Cited by 28 - Related articles - BL Direct - All 4 versions

The diagnosis of ectopic focal hyperinsulinism of infancy with [18F]-dopa positron …

- endojournals.org
K Hussain, M Seppanen, K Nanto-Salonen, NS … - Journal of Clinical …, 2006 - Endocrine Soc
Background: Congenital hyperinsulinism (CHI) is a cause of severe hypoglycemia in the neonatal
and infancy period. Histologically, there are two subtypes with diffuse and focal disease. The
preoperative differentiation of these two forms is very important because the surgical ...
Cited by 23 - Related articles - BL Direct - All 4 versions

Accuracy of [18F] fluorodopa positron emission tomography for diagnosing and …

- endojournals.org
OT Hardy, M Hernandez-Pampaloni, JR Saffer, … - Journal of Clinical …, 2007 - Endocrine Soc
Results: The diagnosis of focal or diffuse HI was correct in 44 of the 50 cases (88%). [ 18 F]DOPA
PET identified focal areas of high uptake of radiopharmaceutical in 18 of 24 patients with focal
disease. The locations of these lesions matched the areas of increased [ 18 F]DOPA ...
Cited by 22 - Related articles - BL Direct - All 3 versions

Molecular mechanisms of neonatal hyperinsulinism


I Giurgea, C Bellanné-Chantelot, M Ribeiro, L Hubert, … - Horm Res, 2006 - content.karger.com
Congenital hyperinsulinism (CHI), characterized by profound hypoglycaemia related to inappropriate
insulin secretion, may be associated histologically with either diffuse insulin hypersecretion or
focal adenomatous hyperplasia, which share a similar clinical presentation, but result ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Current progress in non-invasive imaging of beta cell mass of the endocrine …

- bentham.org [PDF] 
F Souza, M Freeby, K Hultman, N Simpson, … - Current medicinal …, 2006 - ingentaconnect.com
1 Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA 2
Department of Applied Physics and Applied Mathematics, Columbia University, New York, NY
10032, USA 3 Department of Radiology, Columbia University Medical Center, New York, ...
Cited by 20 - Related articles - BL Direct - All 7 versions

Proposal for a standardized protocol for 18F-DOPA-PET (PET/CT) in congenital …


K Mohnike, O Blankenstein, HT Christesen, J De … - Horm Res, 2006 - content.karger.com
Congenital hyperinsulinism (CHI) is characterized by severe hypoglycemia related to inappropriate
insulin release. The long-term outcome of infants with CHI is dependent on an effective prevention
of hypoglycemic episodes to avert the high risk of permanent brain damage [1]. Advances ...
Cited by 19 - Related articles - All 6 versions

The added value of [18 F] fluoro-L-DOPA PET in the diagnosis of hyperinsulinism …

- pubget.com [PDF] 
MJ Ribeiro, N Boddaert, C Bellanné-Chantelot, S … - European Journal of …, 2007 - Springer
Page 1. ORIGINAL ARTICLE The added value of [ 18 F]fluoro- L -DOPA PET in the diagnosis
of hyperinsulinism of infancy: a retrospective study involving 49 children Maria-João Ribeiro &
Nathalie Boddaert & Christine Bellanné-Chantelot & Sandrine Bourgeois & ...
Cited by 14 - Related articles - All 3 versions


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