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Scholar Results 1 - 10 of about 16 citing Sainsbury: Y2Y4 receptor double knockout protects against obesity due to a high-fat diet.... (0.22 sec) 

Neuropeptide Y receptor selective ligands in the treatment of obesity

- endojournals.org
MM Kamiji, A Inui - Endocrine reviews, 2007 - Endocrine Soc
Obesity is a serious public health problem throughout the world, affecting both
developed societies and developing countries. The central nervous system has
developed a meticulously interconnected circuitry in order to keep us fed ...
Cited by 18 - Related articles - BL Direct - All 3 versions

Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis

- jbc.org
PA Baldock, SJ Allison, P Lundberg, NJ Lee, … - Journal of Biological Chemistry, 2007 - ASBMB
The importance of neuropeptide Y (NPY) and Y2 receptors in the regulation of
bone and energy homeostasis has recently been demonstrated. However, the
contributions of the other Y receptors are less clear. Here we show that Y1 ...
Cited by 20 - Related articles - All 5 versions

Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone …


HR Patel, Y Qi, EJ Hawkins, SM Hileman, JK … - Diabetes, 2006 - Am Diabetes Assoc
Neuropeptide Y (NPY) stimulates feeding and weight gain, but deletion of the NPY
gene does not affect food intake and body weight in mice bred on a mixed genetic
background. We reasoned that the orexigenic action of NPY would be evident ...
Cited by 15 - Related articles - BL Direct - All 7 versions

ICV NPY Y1 receptor agonist but not Y5 agonist induces torpor-like hypothermia in cold- …

- physiology.org
KM Pelz, J Dark - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc
The reduced metabolism derived from daily torpor enables numerous small mammals,
including Siberian hamsters, to survive periods of energetic challenge. Little
is known of the neural mechanisms underlying the initiation and expression ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Fasting inhibits the growth and reproductive axes via distinct Y2 and Y4 receptor-mediated …

- endojournals.org
S Lin, EJD Lin, D Boey, NJ Lee, K Slack, MJ … - Endocrinology, 2007 - Endocrine Soc
Neuropeptide Y, a neuropeptide abundantly expressed in the brain, has been
implicated in the regulation of the hypothalamo-pituitary-somatotropic axis and
the hypothalamo-pituitary-gonadotropic axis. Elevated hypothalamic ...
Cited by 3 - Related articles - BL Direct - All 3 versions

Y eat?


MJS Chee, WF Colmers - Nutrition, 2008 - Elsevier
Feeding behavior is tightly regulated by peptidergic transmission within the
hypothalamus. Neuropeptide Y (NPY) is one of the most potent known stimulators
of food intake and has robust effects on the hypothalamic feeding neuronal ...
Cited by 6 - Related articles - All 2 versions

[CITATION] Preclinical developments in antiobesity drugs


SP VICKERS, SC CHEETHAM - Appetite and body weight: integrative systems and the …, 2006 - Academic Press
Cited by 2 - Related articles

NPY Y2 and Y4 receptors selective ligands: promising anti-obesity drugs?


MM Kamiji, A Inui - Current Topics in Medicinal Chemistry, 2007 - ingentaconnect.com
Abstract: Neuropeptide Y (NPY), a potent orexigen peptide widely produced and
distributed in arcuate neurons in the hypothalamus, is a promising candidate for
the control of appetitive ingestive behavior. In mammals, the signaling is ...
Cited by 2 - Related articles - All 3 versions

Y2, Y4 receptors and obesity


EJD Lin, L Zhang, A Sainsbury, H Herzog - Expert Review of Endocrinology and Metabolism, 2007 - ingentaconnect.com
10.1586/17446651.2.2.163 © 2007 Future Drugs Ltd ISSN 1744-6651 163 ... En-Ju
D Lin † , Lei Zhang, Amanda Sainsbury and Herbert Herzog ... † Author for
correspondence The Garvan Institute of Medical Research, Neuroscience ...
Cited by 2 - Related articles - All 3 versions

Synergistic attenuation of obesity by Y2-and Y4-receptor double knockout in ob/ob mice


NJ Lee, RF Enriquez, D Boey, S Lin, K Slack, … - Nutrition, 2008 - Elsevier
Male and female Y24ob triple mutants showed highly significant reductions in
body weight and white adipose tissue mass compared with ob/ob mice. This
reduction in body weight was not evident in Y2ob or Y4ob double mutants, ...
Cited by 1 - Related articles - All 13 versions


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