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Scholar Results 1 - 10 of about 75 citing Battaglia: Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that.... (0.09 sec) 

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans


MG Roncarolo, S Gregori, M Battaglia, R … - Immunol Rev, 2006 - interscience.wiley.com
Summary: Interleukin‐10 (IL‐10)‐secreting T regulatory type 1 (Tr1) cells
are defined by their specific cytokine production profile, which includes the
secretion of high levels of IL‐10 and transforming growth ...
Cited by 269 - Related articles - BL Direct - All 4 versions

Selective survival of naturally occurring human CD4+ CD25+ Foxp3+ regulatory T cells …

- jimmunol.org
L Strauss, TL Whiteside, A Knights, C … - The Journal of Immunology, 2007 - Am Assoc Immnol
Naturally occurring CD4 + CD25 + regulatory T (nTreg) cells are essential for
maintaining T cell tolerance to self Ags. We show that discrimination of human
Treg from effector CD4 + CD25 + non-nTreg cells and their selective ...
Cited by 97 - Related articles - BL Direct - All 5 versions

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but …

- jimmunol.org
HR Turnquist, G Raimondi, AF Zahorchak, … - The Journal of Immunology, 2007 - Am Assoc Immnol
The ability of dendritic cells (DC) to regulate Ag-specific immune responses via
their influence on T regulatory cells (Treg) may be key to their potential as
therapeutic tools or targets for the promotion/restoration of tolerance. In ...
Cited by 58 - Related articles - All 4 versions

Regulatory T cells and transplantation tolerance


S Jiang, RI Lechler, XS He, JF Huang - Human immunology, 2006 - Elsevier
In the past decade, several types of regulatory T cells (Tregs) have been
identified to play a pivotal role in the control of autoimmunity and
transplantation tolerance in rodents and in human beings, including innate ...
Cited by 51 - Related articles - All 4 versions

Induction of tolerance in type 1 diabetes via both CD4+ CD25+ T regulatory cells and T …

- shouxi.net
M Battaglia, A Stabilini, E Draghici, B … - Diabetes, 2006 - Am Diabetes Assoc
Success in developing novel therapies to recommence self-tolerance in
autoimmunity depends on the induction of T regulatory (Tr) cells. Here, we
report that rapamycin combined with interleukin (IL)-10 efficiently blocks ...
Cited by 47 - Related articles - BL Direct - All 5 versions

Immunological Analogy Between Allograft Rejection, Recurrent Abortion and Pre- …


JR Wilczyński - Human immunology, 2006 - Elsevier
There are still controversies concerning the role of immunological mechanisms
engaged both in recurrent abortions (RA) and pre-eclampsia (PE). According to
some opinions, recurrent miscarriage is comparable to organ-specific ...
Cited by 31 - Related articles - All 5 versions

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV- …

- hematologylibrary.org
F Mingozzi, NC Hasbrouck, E Basner- … - Blood, 2007 - bloodjournal.hematologylibrary.org
Adeno-associated virus (AAV)–mediated gene transfer of factor IX (F.IX) to the
liver results in long-term expression of transgene in experimental animals, but
only short-term expression in humans. Loss of F.IX expression is likely due ...
Cited by 30 - Related articles - BL Direct - All 5 versions

CD4 T-regulatory cells: toward therapy for human diseases


SE Allan, R Broady, S Gregori, ME Himmel, N … - Immunological Reviews, 2008 - pt.wkhealth.com
Acknowledgements: We thank Paul Orban for critical reading of the manuscript.
The authors' own research was supported by grants from the Canadian Institutes
for Health Research (CIHR), the National Cancer Institute of Canada, the ...
Cited by 22 - Related articles - All 6 versions

T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts …


T Manigold, V Racanelli - The Lancet Infectious Diseases, 2007 - Elsevier
In the past few years, we have witnessed extraordinary advances in the
understanding of the functions of regulatory T (Treg) cells in immunity against
pathogens. However, controversy exists over the part that these cells play ...
Cited by 21 - Related articles - All 18 versions

Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non- …


J Peng, B Dicker, W Du, F Tang, P Nguyen, T … - Journal of Autoimmunity, 2007 - Elsevier
Immuno-regulatory defects, including a reduction in the number and function of
regulatory T cells, play an important role in the development of autoimmune
diabetes in both humans and non-obese diabetic (NOD) mice. In this study we ...
Cited by 17 - Related articles - All 4 versions


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