- ►endojournals.org MC Jorgensen, J Ahnfelt-Ronne, J Hald, OD … - Endocrine Reviews, 2007 - Endocrine Soc Pancreas morphogenesis and cell differentiation are highly conserved among
vertebrates during fetal development. The pancreas develops through simple
budlike structures on the primitive gut tube to a highly branched organ ... Cited by 34 - Related articles - BL Direct - All 3 versions
EL Edghill, C Bingham, AS Slingerland, JA … - Diabetic Medicine, 2006 - interscience.wiley.com Aim The transcription factor hepatocyte nuclear factor-1beta (HNF-1β) is
expressed in rodent pancreatic progenitor cells, where it is an important member
of the genetic hierarchy that regulates the generation of pancreatic ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►nih.gov JM Oliver-Krasinski, DA Stoffers - Genes & development, 2008 - genesdev.cshlp.org The major forms of diabetes are characterized by pancreatic islet β-cell
dysfunction and decreased β-cell numbers, raising hope for cell replacement
therapy. Although human islet transplantation is a cell-based therapy under ... Cited by 20 - Related articles - All 4 versions
- ►nih.gov PO Wiebe, JD Kormish, VT Roper, Y Fujitani, … - Molecular and cellular biology, 2007 - Am Soc Microbiol The critical pancreatic transcription factor Pdx1 is expressed throughout the
pancreas early but enriched in insulin-producing ß cells postnatally. Previous
studies showed that the 5' conserved promoter regions areas I and II (Pdx1 ... Cited by 18 - Related articles - BL Direct - All 8 versions
- ►endojournals.org L Aguilar-Bryan, J Bryan - Endocrine Reviews, 2008 - Endocrine Soc An explosion of work over the last decade has produced insight into the multiple
hereditary causes of a nonimmunological form of diabetes diagnosed most
frequently within the first 6 months of life. These studies are providing ... Cited by 15 - Related articles - BL Direct - All 6 versions
- ►nih.gov JB Beaudry, CE Pierreux, GP Hayhurst, N … - Molecular and Cellular Biology, 2006 - Am Soc Microbiol During liver development, hepatocytes undergo a maturation process that leads to
the fully differentiated state. This relies at least in part on the coordinated
action of liver-enriched transcription factors (LETFs), but little is known ... Cited by 7 - Related articles - BL Direct - All 7 versions
- ►biologists.org L Lokmane, C Haumaitre, P Garcia-Villalba, … - Development, 2008 - dev.biologists.org Mouse liver induction occurs via the acquisition of ventral endoderm competence
to respond to inductive signals from adjacent mesoderm, followed by hepatic
specification. Little is known about the regulatory circuit involved in ... Cited by 7 - Related articles - All 4 versions
LW Harries - Expert Review of Endocrinology and Metabolism, 2006 - ingentaconnect.com Variation in mRNA processing has the capacity to exert fine control over gene
expression in most cell types. The hepatic nuclear factor genes, like
approximately 74% of the genome, produce multiple transcripts. Hepatic ... Cited by 3 - Related articles - All 3 versions
- ►pubget.com [PDF] Y Wang, BP Flemming, CC Martin, SR Allen, J … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In all the transgenic mice, robust LacZ expression was detected in
newborn mouse islets, but expression became mosaic as animals aged, suggesting
that additional elements are required for the maintenance of IGRP gene ... Cited by 3 - Related articles - BL Direct - All 6 versions
DA Gardner-Stephen, PI Mackenzie - Current Drug Metabolism, 2008 - ingentaconnect.com Abstract: Variations in the capacity to detoxify carcinogens and other
environmental toxins, and to eliminate drugs and waste products of metabolism,
are likely to have significant effects on health and drug efficacy. As the ... Cited by 3 - Related articles - All 2 versions
