- ►nih.gov JM Hughes, EJ Kuiper, I Klaassen, P Canning, AW Stitt, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Advanced glycation end products cause increased CCN family
and extracellular matrix gene expression in the diabetic rodent retina JM Hughes
& EJ Kuiper & I. Klaassen & P. Canning & AW Stitt & J. Van Bezu ... Cited by 18 - Related articles - BL Direct - All 7 versions
R Yang, H LIU, I WILLIAMS, B … - ANNALS-NEW YORK …, 2007 - interscience.wiley.com Abstract : Diabetic retinopathy (DR) commences as a basement membrane disorder with a dramatic
loss of the innate retinal vascular autoregulation. In this process, retinal pericytes, which regulate
endothelial cell proliferation and survival, undergo morphometric changes consistent with ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org Y Behl, P Krothapalli, T Desta, A DiPiazza, S Roy, DT … - American Journal of …, 2008 - ASIP Retinal microvascular cell loss plays a critical role in the pathogenesis of diabetic
retinopathy. To examine this further, type 1 streptozotocin-induced diabetic rats and type 2 Zucker
diabetic fatty rats were treated by intravitreal injection of the tumor necrosis factor-specific ... Cited by 10 - Related articles - BL Direct - All 6 versions
- ►iovs.org EJ Kuiper, JM Hughes, RJ Van Geest, I Vogels, R … - … Ophthalmology & Visual …, 2007 - ARVO PURPOSE. Vascular endothelial growth factor-A (VEGF) causes increased vascular permeability
and leukocyte adhesion in preclinical diabetic retinopathy (PCDR). Another hallmark of PCDR
is thickening of the capillary basement membrane (BM). Recently, VEGF has been shown ... Cited by 9 - Related articles - BL Direct - All 2 versions
T Oshitari, S Roy - Current Drug Therapy, 2007 - ingentaconnect.com Abstract: Diabetic retinopathy and glaucoma are major diseases that cause blindness in a high
percentage of the popula- tion. However, the precise mechanisms involved in the onset and
the progression of these diseases are still not completely known. Recent studies have ... Cited by 4 - Related articles - BL Direct
T Oshitari - Drug Development Research, 2006 - interscience.wiley.com Diabetic retinopathy results from vascular abnormalities, such as an increase in the permeability
of retinal vessels, and retinal neurodegeneration, which are irreversible changes that occur early
in the course of diabetic retinopathy. To block the vascular and neuronal complications ... Cited by 3 - Related articles - BL Direct - All 3 versions
T Oshitari, S Yamamoto, N Hata, S Roy - British Medical Journal, 2008 - bjo.bmj.com Methods: Immunohistochemistry was performed on cryosections obtained from five pairs of normal
and five pairs of age-matched diabetic human retinas. Diabetic eyes had no proliferative diabetic
retinopathy and no histories of photocoagulation or ocular surgery. In this study, ... Cited by 3 - Related articles - BL Direct - All 4 versions
- ►jhc.org EJ Kuiper, R van Zijderveld, P Roestenberg, … - … of Histochemistry and …, 2008 - Histochemical Soc Experimental prevention of BL thickening ameliorated early retinal vascular changes caused
by diabetes (Roy et al. 2003 Go ; Oshitari et al. 2006 Go ). In galactose-fed rats, a model for type
2 diabetes, downregulation of fibronectin synthesis partly prevented retinal BL thickening ... Cited by 3 - Related articles - All 7 versions
