T Seimon, I Tabas - The Journal of Lipid Research, 2009 - ASBMB Macrophage apoptosis is an important feature of atherosclerotic plaque development. Research
directed at understanding the functional consequences of macrophage death in atherosclerosis
has revealed opposing roles for apoptosis in atherosclerotic plaque progression. In early ... Cited by 16 - Related articles - All 4 versions
- ►physiology.org RJ Copeland, JW Bullen, GW Hart - American Journal of …, 2008 - Am Physiological Soc O-linked β-N-acetylglucosamine (O-GlcNAc) is a dynamic posttranslational modification that,
analogous to phosphorylation, cycles on and off serine and/or threonine hydroxyl groups. Cycling
of O-GlcNAc is regulated by the concerted actions of O-GlcNAc transferase and O- ... Cited by 17 - Related articles - All 3 versions
- ►physiology.org Y Wasef, Z Sherif, KA Robinson, MN … - American Journal of …, 2006 - Am Physiological Soc Tribbles 3 (TRB3) is a recently recognized atypical inactive kinase that negatively regulates Akt
activity in hepatocytes, resulting in insulin resistance. Recent reports link TRB3 to nutrient sensing
and regulation of cell survival under stressful conditions. We studied the regulation of ... Cited by 13 - Related articles - BL Direct - All 3 versions
SS Rajan, V Srinivasan, M Balasubramanyam, U … - Indian Journal of Medical …, 2007 - icmr.nic.in The endoplasmic reticulum (ER) is a central organelle entrusted with lipid synthesis, protein
folding and protein maturation. It is endowed with a quality control system that facilitates the recognition
and targeting of aberrant proteins for degradation. When the capacity of this quality ... Cited by 12 - Related articles - View as HTML - BL Direct - All 3 versions
- ►jlr.org W Qiu, RK Avramoglu, AC Rutledge, J Tsai, K … - The Journal of Lipid …, 2006 - ASBMB Glucosamine-induced endoplasmic reticulum (ER) stress was recently shown to specifically
reduce apolipoprotein B-100 (apoB-100) secretion by enhancing the proteasomal degradation
of apoB-100. Here, we examined the mechanisms linking glucosamine-induced ER ... Cited by 10 - Related articles - BL Direct - All 6 versions
- ►endocrinology-journals.org Z Li, T Zhang, H Dai, G Liu, H Wang, Y Sun, … - Journal of …, 2008 - Soc Endocrinology Apoptosis plays a critical role in the diabetic cardiomyopathy, and endoplasmic reticulum stress
(ERS) is one of the intrinsic apoptosis pathways. Previous studies have shown that the endoplasmic
reticulum becomes swollen and dilated in diabetic myocardium, and ERS is involved in ... Cited by 9 - Related articles - BL Direct - All 4 versions
JA Matthews, JL Belof, M Acevedo-Duncan, RL … - Molecular and cellular …, 2007 - Springer Abstract Increased glucose flux through the hexos- amine biosynthetic pathway (HBP) is known
to affect the activity of a number of signal transduction path- ways and lead to insulin
resistance. Although widely studied in insulin responsive tissues, the effect of in- creased ... Cited by 7 - Related articles - BL Direct - All 5 versions
G Liu, Y Sun, Z Li, T Song, H Wang, Y Zhang, Z Ge - … and Biophysical Research …, 2008 - Elsevier Endoplasmic reticulum stress has been suggested to play a crucial role in the pathogenesis
of diabetic complications. However, whether it is involved in the renal injury of diabetic nephropathy
is still not known. We investigated the involvement of ER-associated apoptosis in kidney ... Cited by 7 - Related articles - All 3 versions
V Srinivasan, N Sandhya, R Sampathkumar, S Farooq, … - Clinical Biochemistry, 2007 - Elsevier The mean (± SE) GFAT activity was significantly higher in diabetic (30.22 ± 2.40 pM/mg
protein/min) compared to control subjects (20.10 ± 1.12 pM/mg protein/min) (p < 0.001). Plasma
levels of diabetic patients also exhibited increased lipid peroxidation and protein ... Cited by 6 - Related articles - All 2 versions