- ►nih.gov AP Jayasooriya, ML Mathai, LL Walker, DP … - Science's STKE, 2008 - stke.sciencemag.org Abstract: In addition to its role in the storage of fat, adipose tissue acts as
an endocrine organ, and it contains a functional renin-angiotensin system (RAS).
Angiotensin-converting enzyme (ACE) plays a key role in the RAS by ... Cited by 19 - Related articles - BL Direct - All 11 versions
- ►endocrinology-journals.org E Park, V Wong, X Guan, AI Oprescu, A … - Journal of Endocrinology, 2007 - Soc Endocrinology Recent evidence indicates that inflammatory pathways are causally involved in
insulin resistance. In particular, I B kinase ß (IKKß ), which can impair
insulin signaling directly via serine phosphorylation of insulin receptor ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org PY Mong, C Petrulio, HL Kaufman, Q Wang - The Journal of Immunology, 2008 - Am Assoc Immnol TNF- induces complex signaling events in endothelial cells (ECs), leading to
inflammatory gene transcription and junctional permeability increases. This
study examined the activation of RhoA and Rho kinase induced by TNF- in ... Cited by 11 - Related articles - All 2 versions
- ►mendeley.com [PDF] MA Mori, RC Araújo, FCG Reis, DG Sgai, RG … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Kinin B 1 receptor deficiency in mice (B 1 −/− ) resulted in less
fat content, hypoleptinemia, increased leptin sensitivity, and robust protection
against high-fat diet–induced weight gain. Under high-fat diet, B 1 ... Cited by 6 - Related articles - All 6 versions
- ►physiology.org V Kaddai, T Gonzalez, M Bolla, Y Le … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc NCX 4016 is a nitric oxide (NO)-donating derivative of acetylsalicylic acid. NO
and salicylate, in vivo metabolites of NCX 4016, were shown to be potential
actors in controlling glucose homeostasis. In this study, we evaluated the ... Cited by 4 - Related articles - All 3 versions
P LoGrasso, T Kamenecka - Mini Reviews in Medicinal Chemistry, 2008 - ingentaconnect.com Abstract: Inhibitors of c-jun-N-Terminal Kinase (JNK) have many potential
therapeutic indications ranging from neu- rodegenerative disease, to metabolic
disorders, inflammation, cardiovascular disease, and cancer. This overview ... Cited by 2 - Related articles - All 2 versions
MA Mori, RC Araújo, JB Pesquero - International Immunopharmacology, 2008 - Elsevier Kinins are potent vasoactive and inflammatory peptides generated by kallikreins
in blood and tissues that bind to specific receptors named B 1 and B 2 . On the
other hand, leptin is an adipocytokine that displays broad effects on ... Cited by 1 - Related articles - All 2 versions
CC Juan, CC Lien, CL Chang, YH Huang, LT … - Obesity, 2008 - nature.com Differentiated 3T3-L1 adipocytes were treated for 24 h with 0–10 ng/ml of TNF-
or with 2.5 ng/ml of TNF- for 0–24 h, and then resistin mRNA levels were
measured by northern blotting. To further explore the involvement of nitric ... Cited by 1 - Related articles - All 3 versions
T Kabutoya, J Ishikawa, S Hoshide, K Eguchi, … - Clinical and Experimental Hypertension, 2008 - informahealthcare.com Background. Recently, it was reported that high pulse rate (PR), which was
measured using by self-measured blood pressure (BP) monitoring at home, was
associated with cardiovascular risk. However, the predictor of high PR at ... Related articles - BL Direct - All 4 versions
- ►problemsinanes.com MAS Mori, M Bader, JB Pesquero - Current Opinion in Nephrology and Hypertension, 2008 - journals.lww.com Recent findings: A role for the renin-angiotensin system in the regulation of
adiposity and glucose metabolism has been suggested. Studies using genetically
altered animals not only confirmed the physiological relevance of ... Related articles - BL Direct - All 13 versions