DN Gross, M Wan, MJ Birnbaum - Current Diabetes Reports, 2009 - Springer Forkhead box O (FOXO) transcription factors play an important role in modulating
metabolic func- tions. FOXO is regulated by several modifications, but one of
the most critical is phosphorylation and nuclear exclusion by Akt. Given ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org AJ Weinhaus, LE Stout, NV Bhagroo, TC … - Journal of Endocrinology, 2007 - Soc Endocrinology Glucokinase activity is increased in pancreatic islets during pregnancy and in
vitro by prolactin (PRL). The underlying mechanisms that lead to increased
glucokinase have not been resolved. Since glucose itself regulates ... Cited by 14 - Related articles - BL Direct - All 3 versions
- ►nih.gov JY Lee, O Gavrilova, B Davani, R Na, GW … - BBA-Molecular Cell Research, 2007 - Elsevier In insulinoma cell lines proliferation and insulin gene transcription are
stimulated by growth hormone and prolactin, which convey their signals through
the transcription factors Stat5a and 5b (referred to as Stat5). However, ... Cited by 11 - Related articles - All 4 versions
- ►endojournals.org R Arumugam, E Horowitz, D Lu, JJ Collier, … - Endocrinology, 2008 - Endocrine Soc Carbohydrate metabolism in pregnancy reflects the balance between
counterregulatory hormones, which induce insulin resistance, and lactogenic
hormones, which stimulate β-cell proliferation and insulin production. ... Cited by 4 - Related articles - All 3 versions
LT Dalgaard, N Billestrup, JH Nielsen - Expert Review of Endocrinology and Metabolism, 2008 - ingentaconnect.com Signal transducer and activator of transcription (STAT)5A and -5B are latent
transcription factors activated by cytokines and hormones of the cytokine
family. In pancreatic insulin- secreting β-cells, STAT5A and -5B are ... Cited by 1 - Related articles - All 8 versions
F View - medscape.com The relative importance of STAT5A versus -5B has been and will continue to be
evaluated in β-cells using different approaches, such as STAT5A and -5B single
and double knockout mice and RNA interference in cultures of β-cells and ... Related articles
S as a Repressor, F View - medscape.com Owing to the close genomic localization of STAT5A and -5B, it is not possible to
generate combined knockout mice by interbreeding single knockout mice. Thus,
double knockout STAT5A + B mice were generated by sequential homologous ... Related articles
S as a Repressor, F View - medscape.com The physiological role of these hormones is particularly significant during
pregnancy, as previously mentioned. In pregnancy, the demand for insulin is
markedly increased, in part due to the elevated levels of PL, PRL and GH. ... Related articles
LM He, DJ Sartori, M Teta, LM Opare-Addo, … - Molecular Endocrinology, 2009 - Endocrine Soc The molecular determinants of β-cell mass expansion remain poorly understood.
Cyclin D2 is the major D-type cyclin expressed in β-cells, essential for adult
β-cell growth. We hypothesized that cyclin D2 could be actively regulated ... Related articles - All 3 versions
S as a Repressor, F View - medscape.com Gouilleux F, Moritz D, Humar M et al. Prolactin and interleukin-2 receptors in T
lymphocytes signal through a MGF-STAT5-like transcription factor. Endocrinology
136(12), 5700-5708 (1995). ... Schindler C, Levy DE, Decker T. JAK-STAT ... Related articles
