- ►nih.gov JD Johnson, E Bernal-Mizrachi, EU Alejandro … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences Insulin is both a hormone regulating energy metabolism and a growth factor. We
and others have shown that physiological doses of insulin initiate complex
signals in primary human and mouse β-cells, but the functional ... Cited by 32 - Related articles - BL Direct - All 10 versions
- ►physiology.org F Malavasi, S Deaglio, A Funaro, E Ferrero, AL … - Physiological reviews, 2008 - Am Physiological Soc The membrane proteins CD38 and CD157 belong to an evolutionarily conserved
family of enzymes that play crucial roles in human physiology. Expressed in
distinct patterns in most tissues, CD38 (and CD157) cleaves NAD + and NADP ... Cited by 24 - Related articles - All 3 versions
- ►endojournals.org JL Beith, EU Alejandro, JD Johnson - Endocrinology, 2008 - Endocrine Soc A relative decrease in β-cell mass is key in the pathogenesis of type 1
diabetes, type 2 diabetes, and in the failure of transplanted islet grafts. It
is now clear that β-cell duplication plays a dominant role in the ... Cited by 13 - Related articles - BL Direct - All 5 versions
FE Lund - Molecular Medicine, 2006 - pubmedcentral.nih.gov The 5th international CD38 meeting, held in Torino, Italy, spanned a range of
topics from the role of CD38 as a signaling receptor in lymphocytic tumors to
the importance of CD38-derived metabolites in NAD + metabolism, calcium ... Cited by 12 - Related articles - BL Direct - All 7 versions
- ►fasebj.org MTP Barbosa, SM Soares, CM Novak, D … - The FASEB Journal, 2007 - FASEB Obesity is one of the major health problems of our times. Elucidating the
signaling mechanisms by which high-fat caloric diet induces obesity is critical
for the understanding of this condition and for the development of ... Cited by 11 - Related articles - BL Direct - All 4 versions
DS Luciani, KS Gwiazda, TLB Yang, TB … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Neither RyR nor IP 3 R inhibition, alone or in combination, caused
robust death within 24 h. In contrast, blocking sarco/endoplasmic reticulum
ATPase (SERCA) pumps depleted ER Ca 2+ and induced marked phosphorylation ... Cited by 3 - Related articles - All 3 versions
- ►jbc.org Q Liu, IA Kriksunov, C Moreau, R Graeff, BVL … - Journal of Biological Chemistry, 2007 - ASBMB Cyclic ADP-ribose (cADPR) is a calcium mobilization messenger important for
mediating a wide range of physiological functions. The endogenous levels of
cADPR in mammalian tissues are primarily controlled by CD38, a ... Cited by 1 - Related articles - All 6 versions
- ►problemsinanes.com WJ Arendshorst, TL Thai - Current opinion in nephrology and hypertension, 2009 - journals.lww.com Recent findings: Adenosine diphosphate -ribosyl (ADPR) cyclase and its
endogenous metabolites cyclic adenosine diphosphate-ribose and nicotinic acid
adenine dinucleotide phosphate mobilize intracellular Ca 2+ from ... Cited by 1 - Related articles - All 7 versions