TS Kern - Exp Diabetes Res, 2007 - hindawi.com Diabetes causes metabolic and physiologic abnormalities in the retina, and these changes suggest
a role for inflammation in the development of diabetic retinopathy. These changes include upregulation
of iNOS, COX-2, ICAM-1, caspase 1, VEGF, and NF-κB, increased production of nitric ... Cited by 34 - Related articles - View as HTML - All 12 versions
- ►diabetesjournals.org E Carrasco, C Hernández, A Miralles, P Huguet, J … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—A higher expression of SST was detected in RPE than neuroretina in both
groups. SST mRNA levels and SST-28 immunoreactivity were significantly lower in both RPE
and the neuroretina from diabetic donors compared with nondiabetic donors. These ... Cited by 11 - Related articles - BL Direct - All 4 versions
M Lorenzi - Exp Diabetes Res, 2007 - hindawi.com The polyol pathway is a two-step metabolic pathway in which glucose is reduced to sorbitol,
which is then converted to fructose. It is one of the most attractive candidate mechanisms to
explain, at least in part, the cellular toxicity of diabetic hyperglycemia because (i) it ... Cited by 9 - Related articles - View as HTML - All 15 versions
VR DREL, PAL PACHER, TK ALI, J SHIN, … - … journal of molecular …, 2008 - pubmedcentral.nih.gov This study was aimed at evaluating the potent and specific aldose reductase inhibitor
fidarestat, on diabetes-associated cataract formation, and retinal oxidative-nitrosative stress,
glial activation, and apoptosis. Control and streptozotocin-diabetic rats were treated with ... Cited by 9 - Related articles - BL Direct - All 3 versions
ZA Khan, S Chakrabarti - Exp Diabetes Res, 2007 - hindawi.com Dysfunction and death of microvascular cells and imbalance between the production and the
degradation of extracellular matrix (ECM) proteins are a characteristic feature of diabetic retinopathy
(DR). Glucose-induced biochemical alterations in the vascu- lar endothelial cells may ... Cited by 8 - Related articles - View as HTML - All 15 versions
SA Madsen-Bouterse, RA Kowluru - Reviews in Endocrine & Metabolic …, 2008 - Springer Abstract Retinopathy is one of the most severe ocular complications of diabetes and is a leading
cause of acquired blindness in young adults. The cellular components of the retina are highly
coordinated but very susceptible to the hyperglycemic environment. The microvasculature ... Cited by 6 - Related articles - All 2 versions
A Bhatwadekar, AW Stitt - Expert Review of Ophthalmology, 2007 - ingentaconnect.com Diabetic retinopathy is a major complication of diabetes and several biochemical/molecular mechanisms
have been proposed as key instigators in the initiation and progression of the condition. Accumulating
evidence suggests that formation of advanced glycation end products (AGEs) within the ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org [PDF] CA Gleissner, JM Sanders, J Nadler, K … - … , thrombosis, and vascular …, 2008 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Upregulation of Aldose Reductase During Foam Cell Cited by 5 - Related articles - All 7 versions
M Carlquist, T Frejd, MF Gorwa-Grauslund - Chemico-Biological Interactions, 2008 - Elsevier Human carbonyl reductase 1 (CBR1), that is one of the enzymes responsible for the reduced
efficiency of treatments by the antineoplastic agents anthracyclines, was functionally expressed
in Saccharomyces cerevisiae. CBR1 was purified and kinetically characterised using ... Cited by 2 - Related articles - All 3 versions
