- ►shouxi.net N Turner, CR Bruce, SM Beale, KL Hoehn, T … - Diabetes, 2007 - Am Diabetes Assoc A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has
been proposed as a major factor leading to the accumulation of intramuscular
lipids and their subsequent deleterious effects on insulin action. Here, we ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►physiology.org RA Frost, CH Lang - Journal of Applied Physiology, 2007 - Am Physiological Soc Although the boundaries of skeletal muscle size are fundamentally determined by
genetics, this dynamic tissue also demonstrates great plasticity in response to
environmental and hormonal factors. Recent work indicates that contractile ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►jbc.org S Crunkhorn, F Dearie, C Mantzoros, H Gami, … - Journal of Biological Chemistry, 2007 - ASBMB Peroxisome proliferator activator receptor- coactivator 1 (PGC-1) is a major
candidate gene for diabetes-related metabolic phenotypes, contributing to
decreased expression of nuclear-encoded mitochondrial genes in muscle and ... Cited by 29 - Related articles - All 3 versions
- ►jbc.org T Coll, E Eyre, R Rodriguez-Calvo, X … - Journal of Biological Chemistry, 2008 - ASBMB Here we report that in skeletal muscle cells the contribution to insulin
resistance and inflammation of two common dietary long-chain fatty acids depends
on the channeling of these lipids to distinct cellular metabolic fates. ... Cited by 13 - Related articles - All 3 versions
A Kennedy, K Martinez, CC Chuang, K … - Journal of Nutrition, 2009 - Am Soc Nutrition This review highlights the inflammatory and insulin-antagonizing effects of
saturated fatty acids (SFA), which contribute to the development of metabolic
syndrome. Mechanisms responsible for these unhealthy effects of SFA ... Cited by 12 - Related articles - All 4 versions
- ►nih.gov JL Staudinger, K Lichti - Molecular pharmaceutics, 2007 - pubs.acs.org Liver-enriched nuclear receptors (NRs) collectively function as metabolic and
toxicological “sensors” that mediate liver-specific gene-activation in
mammals. NR-mediated gene-environment interaction regulates important steps ... Cited by 8 - Related articles - All 5 versions
QG Zhou, FF Hou, ZJ Guo, M Liang, GB Wang … - Diabetes/Metabolism Reviews - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 6 - Related articles - All 2 versions
- ►physiology.org LN Sutherland, LC Capozzi, NJ Turchinsky, … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Increasing evidence suggests that reduced adipose tissue mitochondrial content
is associated with the pathogenesis of type 2 diabetes. These investigations
have utilized severely insulin-resistant rodent models. Thus, it is ... Cited by 6 - Related articles - All 3 versions
- ►diabetesjournals.org R Rodríguez-Calvo, L Serrano, T Coll, N … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Chronic activation of the nuclear factor- B (NF- B) in white adipose
tissue leads to increased production of pro-inflammatory cytokines, which are
involved in the development of insulin resistance. It is presently unknown ... Cited by 6 - Related articles - All 5 versions
Y Zhang, C Liu, L Zhu, X Jiang, X Chen, X Qi, … - PLoS ONE, 2007 - pubmedcentral.nih.gov Copyright Zhang et al. This is an open-access article distributed under the
terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original ... Cited by 4 - Related articles - All 6 versions
