- ►jbc.org S Crunkhorn, F Dearie, C Mantzoros, H Gami, WS … - Journal of Biological …, 2007 - ASBMB Peroxisome proliferator activator receptor- coactivator 1 (PGC-1) is a major candidate gene for
diabetes-related metabolic phenotypes, contributing to decreased expression of nuclear-encoded
mitochondrial genes in muscle and adipose tissue. We have demonstrated that muscle ... Cited by 30 - Related articles - All 3 versions
CR Benton, GP Holloway, SE Campbell, Y … - The Journal of …, 2008 - Physiological Soc Peroxisome proliferator-activated receptors (PPARs) alter the expression of genes involved in
regulating lipid metabolism. Rosiglitazone, a PPARγ agonist, induces tissue-specific effects on
lipid metabolism; however, its mode of action in skeletal muscle remains unclear. Since ... Cited by 10 - Related articles - BL Direct - All 6 versions
SA Fraser, I Gimenez, N Cook, I Jennings, M … - Biochemical …, 2007 - pubmedcentral.nih.gov The renal-specific NKCC2 (Na + –K + –2Cl − co-transporter 2) is regulated by changes in phosphorylation
state, however, the phosphorylation sites and kinases responsible have not been fully
elucidated. In the present study, we demonstrate that the metabolic sensing kinase AMPK ... Cited by 10 - Related articles - BL Direct - All 7 versions
- ►physoc.org MJ Zhu, B Han, J Tong, C Ma, JM Kimzey, KR … - The Journal of …, 2008 - Physiological Soc Maternal obesity and over-nutrition give rise to both obstetric problems and neonatal
morbidity. The objective of this study was to evaluate effects of maternal obesity and over-nutrition
on signalling of the AMP-activated protein kinase (AMPK) pathway in fetal skeletal muscle ... Cited by 9 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org N Fujii, RC Ho, Y Manabe, N Jessen, T Toyoda, WL … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Compared with wild-type mice, glucose tolerance in α2i TG mice was slightly impaired
on the control diet and significantly impaired on the high-fat diet. To determine whether the
whole-body glucose intolerance was associated with impaired insulin sensitivity in ... Cited by 5 - Related articles - All 5 versions
- ►nih.gov RC Ho, N Fujii, LA Witters, MF Hirshman, LJ … - … and biophysical research …, 2007 - Elsevier AMP-activated protein kinase (AMPK) is widely recognized as an important regulator of glucose
transport in skeletal muscle. The p38 mitogen-activated protein kinase (MAPK) has been proposed
to be a component of AMPK-mediated signaling. Here we used several different models ... Cited by 5 - Related articles - All 4 versions
- ►reproduction-online.org E Louden, MM Chi, KH Moley - Reproduction, 2008 - Soc Reprod Fertility Maternal insulin resistance results in poor pregnancy outcomes. In vivo and in vitro exposure
of the murine blastocyst to high insulin or IGF1 results in the down-regulation of the IGF1 receptor
(IGF1R). This in turn leads to decreased glucose uptake, increased apoptosis, as well as ... Cited by 3 - Related articles - All 5 versions
DK Coletta, A Sriwijitkamol, E Wajcberg, P Tantiwong, … - Diabetologia, 2009 - Springer Page 1. ARTICLE Pioglitazone stimulates AMP-activated protein kinase signalling and
increases the expression of genes involved in adiponectin signalling, mitochondrial function
and fat oxidation in human skeletal muscle in vivo: a randomised trial ... Cited by 2 - Related articles - All 2 versions
B Kola, A Grossman, M Korbonits - Obesity and metabolism, 2008 - books.google.com Korbonits M (ed): Obesity and Metabolism. Front Horm Res. Basel, Karger, 2008, vol 36, pp
198-211 The Role of AMP-Activated Protein Kinase in Obesity Blerina Kola• Ashley B.
Grossman• Marta Korbonits Department of Endocrinology, Barts and the London, Queen ... Cited by 2 - Related articles - BL Direct - All 5 versions
- ►endojournals.org AW Norris, MF Hirshman, J Yao, N Jessen, N Musi, L … - Endocrinology, 2008 - Endocrine Soc In the setting of insulin resistance, agonists of peroxisome proliferator-activated receptor
(PPAR)- restore insulin action in muscle and promote lipid redistribution. Mice with muscle-specific
knockout of PPAR (MuPPAR KO) develop excess adiposity, despite reduced food intake ... Cited by 2 - Related articles - All 3 versions
