- ►diabetesresearch.org [PDF] A Fornoni, A Pileggi, RD Molano, NY Sanabria, … - Diabetologia, 2008 - Springer Page 1. ARTICLE Inhibition of c-jun N terminal kinase (JNK) improves functional
beta cell mass in human islets and leads to AKT and ... Cited by 14 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org C Evans-Molina, JC Garmey, R Ketchum, KL … - Diabetes, 2007 - Am Diabetes Assoc Glucose is the primary regulator of insulin granule release from pancreatic
islets. In rodent islets, the role of glucose in the acute regulation of insulin
gene transcription has remained unclear, primarily because the abundance ... Cited by 9 - Related articles - BL Direct - All 6 versions
RD Ramracheya, DS Muller, PE Squires, H … - Journal of Pineal Research, 2008 - interscience.wiley.com Abstract: Melatonin is known to inhibit insulin secretion from rodent β-cells
through interactions with cell-surface MT 1 and/or MT 2 receptors, but the
function of this hormone in human islets of Langerhans is not known. In the ... Cited by 9 - Related articles - BL Direct - All 3 versions
A Skowera, RJ Ellis, R Varela-Calviño, S … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Ania Skowera,1,2 Richard J. Ellis,1 Ruben Varela-Calviño,3 Sefina Arif,1 Guo
Cai Huang,4 Cassie Van-Krinks,1 Anna Zaremba,1 Chloe Rackham,1 Jennifer S.
Allen,1 Timothy IM Tree,1 Min Zhao,4 Colin M. Dayan,5 Andrew K. Sewell,6 ... Cited by 9 - Related articles - All 11 versions
JEP Brown, DJ Onyango, SJ Dunmore - FEBS letters, 2007 - Elsevier The adipokine resistin is known to induce insulin resistance in rodent tissues.
Increases in adipose tissue mass are known to have a negative effect on
pancreatic beta-cell function, although the mechanisms are poorly ... Cited by 7 - Related articles - All 7 versions
- ►hspsanddiabetes.com [PDF] PL Hooper - Metabolic syndrome and related disorders, 2007 - liebertonline.com Metabolic syndrome and type 2 diabetes are progressive, indolent, multi-organ
diseases. Un- derstanding the abnormalities of heat shock proteins (HSPs) in
these diseases is paramount to understanding their pathogenesis. In insulin ... Cited by 7 - Related articles - BL Direct - All 5 versions
D Muller, GC Huang, S Amiel, PM Jones, SJ … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin secretion is a highly regulated mechanism
involving a complex insulin-dependent network of communication between alpha,
beta and delta cells. However, whereas the role of insulin in beta cells ... Cited by 6 - Related articles - BL Direct - All 4 versions
K Bouzakri, P Ribaux, A Tomas, G Parnaud, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Protein kinase B/Akt plays a central role in β-cells, but little
is known regarding downstream Akt substrates in these cells. Recently, Rab
GTPase-activating protein AS160, a substrate of Akt, was shown to be ... Cited by 5 - Related articles - BL Direct - All 4 versions
S Persaud, D Muller, P Jones - Biochemical Society Transactions, 2008 - biochemsoctrans.org Studies in transgenic animals, rodent insulin-secreting cell lines and rodent
islets suggest that insulin acts in an autocrine manner to regulate β-cell mass
and gene expression. Very little is known about the in vitro roles played ... Cited by 3 - Related articles - Cached - BL Direct - All 4 versions
C Hinault, J Hu, BF Maier, RG Mirmira, RN … - Diabetes Obes Metab, 2008 - interscience.wiley.com One of the major challenges for developmental biologists and investigators in
the field of diabetes over the last few decades has been to dissect the origin
of pancreatic endocrine cells and to accurately understand the mechanisms ... Cited by 3 - Related articles - All 2 versions
