- ►endojournals.org JM Heward, OJ Brand, JC Barrett, JD Carr- … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Objective: Having previously reported significant association of the T allele of
rs2476601 in a Graves' disease (GD) cohort, we sought to determine whether novel
rheumatoid arthritis-associated SNPs were also contributing to ... Cited by 24 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org C Chelala, S Duchatelet, ML Joffret, R … - Diabetes, 2007 - Am Diabetes Assoc The PTPN22 gene, encoding the lymphoid-specific protein tyrosine phosphatase, a
negative regulator in the T-cell activation and development, has been associated
with the susceptibility to several autoimmune diseases, including type 1 ... Cited by 18 - Related articles - BL Direct - All 4 versions
SA Chung, LA Criswell - Autoimmunity, 2007 - informahealthcare.com The major histocompatilibity complex, and in particular, the human leukocyte
antigen (HLA) region on chromosome 6p21, has been linked to multiple autoimmune
diseases. However, even within the HLA, different genes and alleles are ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org DJ Smyth, JD Cooper, JMM Howson, NM Walker … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The disease association of the common 1858C>T Arg620Trp (rs2476601)
nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine
phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been ... Cited by 16 - Related articles - All 4 versions
B Skinningsrud, ES Husebye, K Gervin, K … - European Journal of Human Genetics, 2008 - nature.com The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently
identified as an important genetic susceptibility factor in several autoimmune
diseases. The increased risk has been broadly explained by the 1858T-allele ... Cited by 15 - Related articles - All 3 versions
AA Zeitlin, MJ Simmonds, SC Gough - CLINICAL ENDOCRINOLOGY-OXFORD-, 2008 - interscience.wiley.com The identification of genes placing individuals at an increased risk for the
development of autoimmune thyroid disease (AITD) has been a slow process.
However, over the last 20 years or so real progress has been made with the ... Cited by 14 - Related articles - BL Direct - All 4 versions
SA Fisher, CM Lewis - Hum Hered, 2008 - content.karger.com Accurate estimation of sample sizes required in a ge- netic association study is
essential before commencing genotyping, to ensure that the study is sufficiently
pow- ered to detect the subtle genetic effects that contribute to most ... Cited by 11 - Related articles - All 6 versions
M Zoledziewska, C Perra, V Orrù, L Moi, P … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The +1858C>T variant, albeit rare in the general Sardinian population
(allele frequency 0.014), was positively associated with type 1 diabetes (P one
tail = 3.7 × 10 −3 ). In contrast, the background haplotype in which ... Cited by 9 - Related articles - BL Direct - All 3 versions
S Liu, H Wang, Y Jin, R Podolsky, MV Reddy, … - Human Molecular Genetics, 2009 - Oxford Univ Press Genome-wide association (GWA) studies revealed a number of single nucleotide
polymorphisms (SNPs) significantly associated with type 1 diabetes (T1D). In an
attempt to confirm some of these candidate associations, we genotyped 2046 ... Cited by 7 - Related articles - All 3 versions
MF Shehata - Cardiovascular diabetology, 2008 - cardiab.com Despite the marked advances in research on insulin resistance (IR) in humans and
animal models of insulin resistance, the mechanisms underlying high salt-induced
insulin resistance remain unclear. Insulin resistance is a multifactorial ... Cited by 5 - Related articles - Cached - All 8 versions