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Scholar Results 1 - 10 of about 28 citing Onengut-Gumuscu: A haplotype-based analysis of the PTPN22 locus in type 1 diabetes. (0.07 sec) 

Association of PTPN22 haplotypes with Graves' disease

- endojournals.org
JM Heward, OJ Brand, JC Barrett, JD Carr- … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Objective: Having previously reported significant association of the T allele of
rs2476601 in a Graves' disease (GD) cohort, we sought to determine whether novel
rheumatoid arthritis-associated SNPs were also contributing to ...
Cited by 24 - Related articles - BL Direct - All 4 versions

PTPN22 R620W functional variant in type 1 diabetes and autoimmunity related traits

- diabetesjournals.org
C Chelala, S Duchatelet, ML Joffret, R … - Diabetes, 2007 - Am Diabetes Assoc
The PTPN22 gene, encoding the lymphoid-specific protein tyrosine phosphatase, a
negative regulator in the T-cell activation and development, has been associated
with the susceptibility to several autoimmune diseases, including type 1 ...
Cited by 18 - Related articles - BL Direct - All 4 versions

PTPN22: its role in SLE and autoimmunity


SA Chung, LA Criswell - Autoimmunity, 2007 - informahealthcare.com
The major histocompatilibity complex, and in particular, the human leukocyte
antigen (HLA) region on chromosome 6p21, has been linked to multiple autoimmune
diseases. However, even within the HLA, different genes and alleles are ...
Cited by 17 - Related articles - BL Direct - All 4 versions

PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a …

- diabetesjournals.org
DJ Smyth, JD Cooper, JMM Howson, NM Walker … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—The disease association of the common 1858C>T Arg620Trp (rs2476601)
nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine
phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been ...
Cited by 16 - Related articles - All 4 versions

Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease


B Skinningsrud, ES Husebye, K Gervin, K … - European Journal of Human Genetics, 2008 - nature.com
The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently
identified as an important genetic susceptibility factor in several autoimmune
diseases. The increased risk has been broadly explained by the 1858T-allele ...
Cited by 15 - Related articles - All 3 versions

Genetic developments in autoimmune thyroid disease: an evolutionary process


AA Zeitlin, MJ Simmonds, SC Gough - CLINICAL ENDOCRINOLOGY-OXFORD-, 2008 - interscience.wiley.com
The identification of genes placing individuals at an increased risk for the
development of autoimmune thyroid disease (AITD) has been a slow process.
However, over the last 20 years or so real progress has been made with the ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Power of genetic association studies in the presence of linkage disequilibrium and allelic …


SA Fisher, CM Lewis - Hum Hered, 2008 - content.karger.com
Accurate estimation of sample sizes required in a ge- netic association study is
essential before commencing genotyping, to ensure that the study is sufficiently
pow- ered to detect the subtle genetic effects that contribute to most ...
Cited by 11 - Related articles - All 6 versions

Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 …


M Zoledziewska, C Perra, V Orrù, L Moi, P … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The +1858C>T variant, albeit rare in the general Sardinian population
(allele frequency 0.014), was positively associated with type 1 diabetes (P one
tail = 3.7 × 10 −3 ). In contrast, the background haplotype in which ...
Cited by 9 - Related articles - BL Direct - All 3 versions

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene …


S Liu, H Wang, Y Jin, R Podolsky, MV Reddy, … - Human Molecular Genetics, 2009 - Oxford Univ Press
Genome-wide association (GWA) studies revealed a number of single nucleotide
polymorphisms (SNPs) significantly associated with type 1 diabetes (T1D). In an
attempt to confirm some of these candidate associations, we genotyped 2046 ...
Cited by 7 - Related articles - All 3 versions

Important genetic checkpoints for insulin resistance in salt-sensitive(S) Dahl rats


MF Shehata - Cardiovascular diabetology, 2008 - cardiab.com
Despite the marked advances in research on insulin resistance (IR) in humans and
animal models of insulin resistance, the mechanisms underlying high salt-induced
insulin resistance remain unclear. Insulin resistance is a multifactorial ...
Cited by 5 - Related articles - Cached - All 8 versions


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