- ►cell.com EJP de Koning, S Bonner-Weir, TJ Rabelink - Trends in Pharmacological Sciences, 2008 - Elsevier Type 2 diabetes is characterized by progressive β-cell dysfunction and a
reduction in β-cell mass. Pancreatic islets are a target for adverse effectors
such as high concentrations of glucose, pro-inflammatory cytokines and ... Cited by 11 - Related articles - All 4 versions
LR Nyman, KS Wells, WS Head, M McCaughey, … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov The pancreatic islets of Langerhans are highly vascularized micro-organs that
play a key role in the regulation of blood glucose homeostasis. The specific
arrangement of endocrine cell types in islets suggests a coupling between ... Cited by 5 - Related articles - All 7 versions
JA Ehses, S Calderari, JC Irminger, P … - Current Immunology Reviews, 2007 - ingentaconnect.com 1 CNRS UMR 7059, Université Paris 7-D Diderot, Paris, France 2 Department of
Internal Medicine, Division of Endocrinology & Diabetes, University Hospital of
Zürich and Center for Integrative Human Physiology, Zürich, Switzerland 3 ... Cited by 4 - Related articles - BL Direct
- ►cshlp.org J Zehetner, C Danzer, S Collins, K Eckhardt, … - Genes & Development, 2008 - genesdev.cshlp.org Insulin secretion from pancreatic β cells is stimulated by glucose metabolism.
However, the relative importance of metabolizing glucose via mitochondrial
oxidative phosphorylation versus glycolysis for insulin secretion remains ... Cited by 2 - Related articles - All 6 versions
- ►nih.gov MV Chakravarthy, Y Zhu, MB Wice, T … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—FASDEL mice did not manifest catch-up growth or insulin resistance.
β-Cell mass and insulin secretion were strikingly increased in young FASDEL
mice, but β-cell failure and diabetes occurred with age. FASDEL β-cells ... Cited by 2 - Related articles - All 4 versions
- ►amjpathol.org E Favaro, I Miceli, B Bussolati, M Schimitt- … - American Journal of Pathology, 2008 - ASIP Pancreatic islet microendothelium and β cells exhibit an interdependent
physical and functional relationship. In this study, we analyzed the effect of
chronic hyperglycemia on human pancreatic islet microendothelial cells as ... Cited by 1 - Related articles - All 4 versions
M Iwase, Y Uchizono, S Nohara, N Sasaki, K … - Scandinavian Journal of Clinical & Laboratory …, 2009 - informahealthcare.com Objective. Renin‐angiotensin system inhibitors are reported to be beneficial
in delaying the onset of diabetes mellitus. Since islet blood hyperperfusion
during hyperglycaemia may be detrimental to endothelium in pancreatic ... Cited by 1 - Related articles - All 5 versions
- ►physiology.org HE Bates, A Sirek, MA Kiraly, JTY Yue, MC … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Intermittent restraint stress delays hyperglycemia in ZDF rats better than pair
feeding. We hypothesized that intermittent stress would preserve β-cell mass
through distinct mechanisms from food restriction. We studied temporal ... Cited by 1 - Related articles - All 3 versions
