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Scholar Results 1 - 10 of about 35 citing Szabó: Poly (ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic.... (0.09 sec) 

Clinical experience with tight glucose control by intensive insulin therapy

- critcaremed.org
JC Preiser, P Devos - Critical Care Medicine, 2007 - pdfs.journals.lww.com
Furthermore, this simple and easily avail- able modality of treatment seemed
even more appealing when the associated healthcare resource utilization was
calcu- lated and found advantageous (4). Simultaneously, new insights of ...
Cited by 44 - Related articles - BL Direct - All 12 versions

[PDF] Activated protein C protects against diabetic nephropathy by inhibiting endothelial and …


B Isermann, IA Vinnikov, T Madhusudhan, S … - Nature medicine, 2007 - basicmed.med.ncku.edu.tw
Data providing direct evidence for a causative link between endothelial
dysfunction, microvascular disease and diabetic end-organ damage are scarce.
Here we show that activated protein C (APC) formation, which is regulated ...
Cited by 46 - Related articles - View as HTML - BL Direct - All 5 versions

[PDF] The Notch pathway in podocytes plays a role in the development of glomerular disease


T Niranjan, B Bielesz, A Gruenwald, MP … - Nature - susztaklab.com-a.googlepages.com
Albuminuria associated with sclerosis of the glomerulus leads to a progressive
decline in renal function affecting millions of people. Here we report that
activation of the Notch pathway, which is critical in glomerular ...
Cited by 21 - Related articles - View as HTML - BL Direct - All 5 versions

Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice

- academia.edu [PDF] 
I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, … - Experimental Neurology, 2007 - Elsevier
Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia,
and impaired nitrergic innervation in animal models of Type 1 diabetes. The role
for reactive nitrogen species in Type 2 diabetes-associated neuropathy ...
Cited by 19 - Related articles - All 5 versions

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and …


IG Obrosova, W Xu, VV Lyzogubov, O Ilnytska, … - Free Radical Biology and Medicine, 2008 - Elsevier
Evidence that poly(ADP-ribose) polymerase (PARP) activation plays an important
role in diabetic complications is emerging. This study evaluated the role of
PARP in rat and mouse models of advanced diabetic neuropathy. The orally ...
Cited by 15 - Related articles - All 3 versions

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin- …


VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov
Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ...
Cited by 13 - Related articles - All 6 versions

Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, …


VR DREL, PAL PACHER, TK ALI, J SHIN, U … - International journal of molecular medicine, 2008 - pubmedcentral.nih.gov
This study was aimed at evaluating the potent and specific aldose reductase
inhibitor fidarestat, on diabetes-associated cataract formation, and retinal
oxidative-nitrosative stress, glial activation, and apoptosis. Control and ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction


C Szabo - Br J Pharmacol, 2009 - interscience.wiley.com
Here we overview the role of reactive nitrogen species (nitrosative stress) and
associated pathways in the pathogenesis of diabetic vascular complications.
Increased extracellular glucose concentration, a principal feature of ...
Cited by 8 - Related articles - All 3 versions

New insights into structural patterns encountered in glomerulosclerosis


M LeHir, W Kriz - Current Opinion in Nephrology and Hypertension, 2007 - journals.lww.com
Purpose of review The term 'focal segmental glomerulosclerosis' covers a variety
of diseases with different histopathological patterns. There is a need for clues
to interpret histological findings in terms of etiology. Studies in ...
Cited by 6 - Related articles - BL Direct - All 6 versions

PARP activation and the alteration of vasoactive factors and extracellular matrix protein in …


B Xu, J Chiu, B Feng, S Chen, S Chakrabarti - Diabetes/Metabolism Reviews - interscience.wiley.com
The development of diabetic complications is associated with increased oxidative
stress which may damage DNA leading to the activation of nuclear enzyme poly
(ADP-ribose) polymerase (PARP). PARP overactivation may further exacerbate ...
Cited by 6 - Related articles - All 4 versions


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