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Scholar Results 1 - 10 of about 31 citing Drel: The Leptin-Deficient (ob/ob) Mouse. (0.08 sec) 

High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity

- shouxi.net
IG Obrosova, O Ilnytska, VV Lyzogubov, IA … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—HFD-fed mice developed obesity, increased plasma FFA and insulin
concentrations, and impaired glucose tolerance. They also had motor and sensory
nerve conduction deficits, tactile allodynia, and thermal hypoalgesia in ...
Cited by 20 - Related articles - BL Direct - All 6 versions

Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice

- academia.edu [PDF] 
I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, … - Experimental Neurology, 2007 - Elsevier
Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia,
and impaired nitrergic innervation in animal models of Type 1 diabetes. The role
for reactive nitrogen species in Type 2 diabetes-associated neuropathy ...
Cited by 19 - Related articles - All 5 versions

The physiology of obese-hyperglycemic mice [ob/ob mice].


P Lindström - TheScientificWorldJOURNAL, 2007 - thescientificworld.com
Page 1. Review Article TheScientificWorldJOURNAL (2007) 7, 666–685 ISSN
1537-744X; DOI 10.1100/tsw.2007.117 ©2007 with author. ...
Cited by 20 - Related articles - All 3 versions

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and …


IG Obrosova, W Xu, VV Lyzogubov, O Ilnytska, … - Free Radical Biology and Medicine, 2008 - Elsevier
Evidence that poly(ADP-ribose) polymerase (PARP) activation plays an important
role in diabetic complications is emerging. This study evaluated the role of
PARP in rat and mouse models of advanced diabetic neuropathy. The orally ...
Cited by 15 - Related articles - All 3 versions

Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin- …

- physiology.org
IG Obrosova, VR Drel, CL Oltman, N Mashtalir … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Evidence for important roles of the highly reactive oxidant peroxynitrite in
diabetic complications is emerging. We evaluated the role of peroxynitrite in
early peripheral neuropathy and vascular dysfunction in STZ-diabetic rats. ...
Cited by 16 - Related articles - BL Direct - All 5 versions

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin- …


VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov
Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ...
Cited by 13 - Related articles - All 6 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ...
Cited by 11 - Related articles - All 2 versions

Evaluation of the peroxynitrite decomposition catalyst Fe (III) tetra-mesitylporphyrin …


VR Drel, P Pacher, I Vareniuk, IA Pavlov, O … - International journal of molecular medicine, 2007 - pubmedcentral.nih.gov
Whereas the important role of free radicals in diabetes-associated complications
is well established, the contributions of the highly reactive oxidant
peroxynitrite have not been properly explored. The present study used a ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via …


M Tsuda, H Ueno, A Kataoka, H Tozaki-Saitoh … - Glia, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 7 - Related articles - BL Direct - All 3 versions

The kinin B1 receptor antagonist SSR240612 reverses tactile and cold allodynia in an …


JP Dias, MA Ismael, M Pilon, J de Champlain, … - British journal of pharmacology, 2007 - pubmedcentral.nih.gov
Glucose-fed rats exhibited tactile and cold allodynia, increases in systolic
blood pressure and higher plasma levels of insulin and glucose, at 12 weeks.
SSR240612 blocked tactile and cold allodynia at 3 h (ID 50 =5.5 and 7.1 mg ...
Cited by 7 - Related articles - BL Direct - All 5 versions


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