K Reue, P Zhang - FEBS letters, 2008 - Elsevier The prevalence of obesity in the western world has focused attention on factors
that influence triglyceride biosynthesis, storage, and utilization. Members of
the lipin protein family have a newly discovered enzymatic role in ... Cited by 25 - Related articles - All 10 versions
- ►jlr.org B Manmontri, M Sariahmetoglu, J Donkor, MB … - The Journal of Lipid Research, 2008 - ASBMB Glucocorticoids (GCs) increase hepatic phosphatidate phosphatase (PAP1)
activity. This is important in enhancing the liver's capacity for storing fatty
acids as triacylglycerols (TAGs) that can be used subsequently for ... Cited by 13 - Related articles - All 4 versions
- ►endojournals.org J Donkor, LM Sparks, H Xie, SR Smith, K … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: In healthy young men, lipin-1 expression was positively correlated with
insulin sensitivity (R 2 = 0.22; P < 0.01), insulin-stimulated respiratory
quotient (R 2 = 0.16; P < 0.01), and maximal oxygen consumption during ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org Z Chen, MC Gropler, J Norris, JC Lawrence Jr, … - Arteriosclerosis, thrombosis, and vascular biology, 2008 - Am Heart Assoc Methods and Results— Rates of TAG synthesis were not impaired in hepatocytes
isolated from adult lipin 1–deficient (fld) mice and were actually increased
in 14-day-old fld mice. Additionally, compared to littermate controls, ... Cited by 6 - Related articles - All 8 versions
- ►physiology.org J Koska, E Ortega, C Bogardus, J Krakoff, JC … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Suppression of lipid oxidation (L ox ) by insulin is impaired in obesity and
type 2 diabetes mellitus (T2DM). Here we tested whether high L ox represents a
primary or acquired characteristic in the pathogenesis of T2DM. ... Cited by 5 - Related articles - BL Direct - All 4 versions
- ►endojournals.org [PDF] J Donkor, LM Sparks, H Xie, SR Smith, K … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Page 1. 1 Adipose tissue lipin-1 expression is correlated with PPARα gene
expression and insulin sensitivity in healthy young men a ... Cited by 4 - Related articles
KA Fawcett, N Grimsey, RJF Loos, E Wheeler, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Loss of lipin 1 activity causes lipodystrophy and insulin
resistance in the fld mouse, and LPIN1 expression and common genetic variation
were recently suggested to influence adiposity and insulin sensitivity in ... Cited by 3 - Related articles - All 6 versions
K Takeuchi, K Reue - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc Triacylglycerol (TAG) synthesis and storage in tissues such as adipose tissue
and liver have important roles in metabolic homeostasis. The molecular
identification of genes encoding enzymes that catalyze steps in TAG ... Cited by 2 - Related articles - All 4 versions
H Huang, MA Frohman - BBA-Molecular and Cell Biology of Lipids, 2009 - Elsevier Regulated production and elimination of the signaling lipids phosphatidic acid
(PA), diacylglycerol (DAG), and phosphatidylinositol 4,5-bisphosphate (PI4,5P 2
) creates a complex and interconnected signaling network that modulates a ... Cited by 1 - Related articles - All 2 versions
K Reue - Fatty Acid and Lipotoxicity in Obesity and Diabetes, 2007 - books.google.com The role of lipin 1 in adipogenesis and lipid metabolism Karen Reue Department
of Human Genetics, David Geffen School of Medicine, University of California,
Los Angeles, CA 90095, USA Abstract. In conditions such as obesity and ... Cited by 1 - Related articles - BL Direct - All 3 versions
