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Scholar Results 1 - 10 of about 18 citing Tiittanen: Insulin treatment in patients with type 1 diabetes induces upregulation of regulatory.... (0.09 sec) 

Autoimmune mechanisms in type 1 diabetes


M Knip, H Siljander - Autoimmunity Reviews, 2008 - Elsevier
Type 1 diabetes (T1D) is perceived as a chronic immune-mediated disease with a
subclinical prodromal period characterized by selective loss of
insulin-producing β-cells in the pancreatic islets in genetically ...
Cited by 24 - Related articles - All 2 versions

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies …

- thelancet.com
K Näntö-Salonen, A Kupila, S Simell, H … - The Lancet, 2008 - Elsevier
At three university hospitals in Turku, Oulu, and Tampere (Finland), we analysed
cord blood samples of 116 720 consecutively born infants, and 3430 of their
siblings, for the HLA-DQB1 susceptibility alleles for type 1 diabetes. 17 ...
Cited by 18 - Related articles - All 20 versions

IL-23/IL-17 immunity as a hallmark of Crohn's disease


V Hölttä, P Klemetti, T Sipponen, M … - Inflamm Bowel Dis, 2008 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 15 - Related articles - All 2 versions

Immunological responses to exogenous insulin

- endojournals.org
SE Fineberg, TT Kawabata, D Finco-Kent, RJ … - Endocrine Reviews, 2007 - Endocrine Soc
Regardless of purity and origin, therapeutic insulins continue to be immunogenic
in humans. However, severe immunological complications occur rarely, and less
severe events affect a small minority of patients. Insulin autoantibodies ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Combined insulin B: 9-23 self-peptide and polyinosinic–polycytidylic acid accelerate …


K Fukushima, N Abiru, Y Nagayama, M … - Biochemical and Biophysical Research …, 2008 - Elsevier
Insulin peptide B:9-23 is a major autoantigen in type 1 diabetes. Combined
treatment with B:9-23 peptide and polyinosinic–polycytidylic acid (poly I:C),
but neither alone, induce insulitis in normal BALB/c mice. In contrast, the ...
Cited by 6 - Related articles - All 3 versions

Diverse foxp3 expression in children with type 1 diabetes and celiac disease


A Kivling, L Nilsson, K Fälth-Magnusson, S … - System, 1927 - interscience.wiley.com
Imbalance between different types of T lymphocytes, such as T helper (Th) and
regulatory T cells (Tregs), has been reported to play a part in the pathogenesis
behind such autoimmune diseases as type 1 diabetes (T1D) and celiac disease ...
Cited by 2 - Related articles - All 4 versions

Effect of metabolic control on interferon-gamma and interleukin-10 production by peripheral …


MC Foss-Freitas, NT Foss, EA Donadi, MC … - Brazilian Journal of Medical and Biological Research, 2007 - SciELO Brasil
The objective of the present study was to evaluate the production of cytokines,
interferon-g (INF-g) and interleukin-10 (IL-10), in cultures of peripheral blood
mononuclear cells (PBMC) from type 1 and type 2 diabetic patients and to ...
Cited by 1 - Related articles - Cached - BL Direct - All 5 versions

N-3 Polyunsaturated Fatty Acids Modulate In-Vitro T Cell Function in Type I Diabetic Patients


SA Merzouk, M Saker, KB Reguig, N … - Lipids, 2008 - Springer
Abstract In this work, we assessed the in-vitro effects of eicosapentaenoic acid
(EPA; C20:5n-3) and docosahexae- noic acid (DHA; C22:6n-3) (final concentration,
15 μM) on T cell blastogenesis, interleukin-2 and -4 (IL-2, IL-4) ...
Cited by 1 - Related articles - BL Direct - All 3 versions

Recent insights into CD4+ T-cell specificity and function in Type 1 diabetes


SI Mannering, TC Brodnicki - Expert Review of Clinical Immunology, 2007 - ingentaconnect.com
† Author for correspondence Autoimmunity & Transplantation Division, The
Walter & Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville
Victoria 3050, Australia Tel.: +61 393 452 457 Fax: +61 393 470 852 ...
Cited by 1 - Related articles - All 3 versions

Update on ICOS: A Possible Target for Turning-Off Autoimmunity


P Sakthivel - Recent Patents on Endocrine, Metabolic &# 38; …, 2009 - ingentaconnect.com
Received: June 3, 2009; Accepted: June 25, 2009; Revised: July 15, 2009
Abstract: Inducible Co-stimulator (ICOS) is one of the co-stimulatory molecules
that are unregulated within hours after TCR engagement. The interaction ...
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