G Muccioli, A Baragli, R Granata, M Papotti, E … - Neuroendocrinology, 2007 - content.karger.com Ghrelin is a gastric polypeptide displaying strong GH-releasing activity by
activation of the type 1a GH secretagogue receptor (GHS-R1a) located in the
hypothalamus-pituitary axis. GHS-R1a is a G-protein-coupled receptor that, ... Cited by 21 - Related articles - BL Direct - All 4 versions
K Dezaki, M Kakei, T Yada - Diabetes, 2007 - Am Diabetes Assoc Ghrelin reportedly serves as a physiological regulator of insulin release. This
study aimed to explore signaling mechanisms for insulinostatic ghrelin action in
islet β-cells, with special attention to heterotrimeric GTP-binding ... Cited by 17 - Related articles - BL Direct - All 3 versions
S Edfalk, P Steneberg, H Edlund - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The G-protein–coupled receptor Gpr40 is expressed in β-cells
where it contributes to free fatty acid (FFA) enhancement of glucose-stimulated
insulin secretion (1–4). However, other sites of Gpr40 expression, ... Cited by 15 - Related articles - All 4 versions
P Wiedmer, R Nogueiras, F Broglio, D D' … - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov The high prevalence of obesity and diabetes will lead to higher rates of
morbidity and mortality. The search for drugs to treat these metabolic disorders
has, therefore, intensified. The stomach-derived peptide ghrelin regulates ... Cited by 14 - Related articles - BL Direct - All 3 versions
H Zhao, GL Liu, QY Wang, LY Ding, H Cai, HH … - Biochemical and biophysical research communications, 2007 - Elsevier Endothelial dysfunction is thought to be a major cause of vascular complications
in diabetes. Our research shows that ghrelin attenuates high glucose-induced
apoptosis in cultured human umbilical vein endothelial cells (ECV-304). ... Cited by 11 - Related articles - All 4 versions
- ►physiology.org C Gauna, RM Kiewiet, JA Janssen, B van de … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Acylated and unacylated ghrelin (AG and UAG) are gut hormones that exert
pleiotropic actions, including regulation of insulin secretion and glucose
metabolism. In this study, we investigated whether AG and UAG ... Cited by 9 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org ET Vestergaard, LC Gormsen, N Jessen, S … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Ghrelin is a gut-derived peptide and an endogenous ligand for the
growth hormone (GH) secretagogue receptor. Exogenous ghrelin stimulates the
release of GH (potently) and adrenocorticotropic hormone (ACTH) ... Cited by 9 - Related articles - All 9 versions
- ►nursing2008.com MM Kamiji, A Inui - Current Opinion in Clinical Nutrition & Metabolic Care, 2008 - journals.lww.com Recent findings: Numerous studies have demonstrated potential beneficial effects
exerted by ghrelin in a number of diseases associated with wasting. Besides
ghrelin's orexigenic effect, anabolic as well as anti-inflammatory activity ... Cited by 6 - Related articles - All 4 versions
- ►cell.com O Gualillo, F Lago, C Dieguez - Trends in Pharmacological Sciences, 2008 - Elsevier The acyltransferase that catalyzes ghrelin octanoylation has recently been
identified as ghrelin O-acyltransferase (GOAT). GOAT belongs to a family of
membrane-bound O-acyltransferases (MBOATs). GOAT covalently links a medium ... Cited by 6 - Related articles - All 4 versions
- ►bentham.org [PDF] T Yada, K Dezaki, H Sone, M Koizumi, B … - Current diabetes reviews, 2008 - ingentaconnect.com 1 Division of Integrative Physiology, Department of Physiology, Jichi Medical
University School of Medicine, Yakushiji 3311-1, Shi- motsuke, Tochigi 329-0498,
Japan; 2 Department of Human Life and Environmental Science, Niigata ... Cited by 8 - Related articles - All 7 versions
