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Scholar Results 1 - 10 of about 53 citing Munoz: Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with.... (0.08 sec) 

TCF7L2 polymorphisms modulate proinsulin levels and β-cell function in a British Europid …


RJF Loos, PW Franks, RW Francis, I Barroso, … - Diabetes, 2007 - Am Diabetes Assoc
Rapidly accumulating evidence shows that common T-cell transcription factor
(TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown
mechanisms. We examined the association between four TCF7L2 single ...
Cited by 53 - Related articles - BL Direct - All 8 versions

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 …

- pubget.com [PDF] 
J Wang, J Kuusisto, M Vänttinen, T Kuulasmaa … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Variants of transcription factor 7-like 2 (TCF7L2) gene predict
conversion to type 2 diabetes in the Finnish Diabetes ...
Cited by 49 - Related articles - BL Direct - All 4 versions

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) …

- diabetesjournals.org
YC Chang, TJ Chang, YD Jiang, SS Kuo, KC … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—The previously reported SNPs rs7903146 T- and rs12255372 T-alleles of
the TCF7L2 gene were rare and were not associated with type 2 diabetes in a
Chinese population, which may attribute to the low frequencies of these two ...
Cited by 43 - Related articles - BL Direct - All 4 versions

Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals

- nih.gov
RM Freathy, MN Weedon, A Bennett, E … - The American Journal of Human Genetics, 2007 - Elsevier
The role of genes in normal birth-weight variation is poorly understood, and it
has been suggested that the genetic component of fetal growth is small. Type 2
diabetes genes may influence birth weight through maternal genotype, by ...
Cited by 42 - Related articles - BL Direct - All 9 versions

The new type 2 diabetes gene TCF7L2

- utah.edu [PDF] 
JC Florez - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com
Purpose of review Common variants in the gene that encodes the transcription
factor 7-like 2 (TCF7L2) have been strongly associated with type 2 diabetes.
This highly reproducible association may uncover novel mechanisms of ...
Cited by 36 - Related articles - BL Direct - All 4 versions

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: …


JC Florez - Diabetologia, 2008 - Springer
Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ...
Cited by 31 - Related articles - BL Direct - All 3 versions

Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis …

- pubget.com [PDF] 
SC Elbein, WS Chu, SK Das, A Yao- … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis We sought to determine: (1) the role of previously
described transcription factor 7-like 2 (TCF7L2) variants in type 2 diabetes in
African American individuals and in participants of European ancestry; (2) ...
Cited by 31 - Related articles - BL Direct - All 6 versions

Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes …

- endojournals.org
MCY Ng, CHT Tam, VKL Lam, WY So, RCW … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Results: Two of the previously reported risk alleles at rs11196205 (C) and
rs7903146 (T) were rare in Chinese (0.013 and 0.024, respectively, in controls).
Rs11196205 was associated with T2D [odds ratio (OR) [95% confidence ...
Cited by 30 - Related articles - BL Direct - All 5 versions

The importance of TCF7L2.

- prsjournal.net
MN Weedon - Diabetic Medicine, 2007 - prsjournal.net
After many years of frustratingly limited success, the genetic architecture of
Type 2 diabetes is finally being uncovered. Recent genome-wide association
studies have identified novel genes predisposing to Type 2 diabetes, which ...
Cited by 25 - Related articles - Cached - BL Direct - All 5 versions

The rs12255372 (G/T) and rs7903146 (C/T) polymorphisms of the TCF7L2 gene are associated …

- mdrf-eprints.in [PDF] 
D Bodhini, V Radha, M Dhar, N Narayani, V … - Metabolism, 2007 - Elsevier
One thousand thirty-eight normal glucose-tolerant and 1031 type 2 diabetic
subjects selected from the Chennai Urban Rural Epidemiology Study were genotyped
using polymerase chain reaction-restriction fragment length polymorphism ...
Cited by 22 - Related articles - All 11 versions


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