- ►slas.ac.cn [PDF] X Xu, J D'Hoker, G Stange, S Bonné, N De Leu, X Xiao, … - Cell, 2008 - Elsevier Novel strategies in diabetes therapy would obviously benefit from the use of beta (β) cell
stem/progenitor cells. However, whether or not adult β cell progenitors exist is one of the most
controversial issues in today's ... Cited by 104 - Related articles - All 9 versions
- ►biologists.org LC Murtaugh - Development, 2007 - dev.biologists.org The development of insulin-producing pancreatic beta (ß)-cells represents the culmination of a
complex developmental program. Cells of the posterior foregut assume a pancreatic identity, cells
within the expanding pancreatic ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►cell.com P Akpinar, S Kuwajima, J Krützfeldt, M Stoffel - Cell Metabolism, 2005 - Elsevier The signals and molecular mechanisms that regulate the replication of terminally differentiated β
cells are unknown. Here, we report the identification and characterization of transmembrane protein
27 (Tmem27, collectrin) in ... Cited by 40 - Related articles - All 12 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative lack of
insulin-producing β cells, respectively. Reconstitution of a functional β-cell mass by cell
therapy – using organ donor ... Cited by 27 - Related articles - BL Direct - All 6 versions
M Peshavaria, BL Larmie, J Lausier, B Satish, A … - Diabetes, 2006 - Am Diabetes Assoc The pancreatic β-cell has a substantial capacity to functionally compensate in response to
physiological and pathophysiological changes in tissue insulin requirements. A fundamental aspect of
this response is the dynamic ... Cited by 24 - Related articles - BL Direct - All 5 versions
TG Fellous, NJ Guppy, M Brittan, MR … - Diabetes/Metabolism … - interscience.wiley.com In the twenty-first century, diabetic patients are likely to be one of the major beneficiaries from
the advancement of regenerative medicine through cellular therapies. Though the existence of a
specific self-renewing stem cell ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►alphamedpress.org M Ta, Y Choi, F Atouf, CH Park, N Lumelsky - Stem Cells, 2006 - AlphaMed Press Application of pancreatic islet transplantation to treatment of diabetes is severely hampered by the
inadequate islet supply. This problem could in principle be overcome by generating islet cells from
adult pancreas in vitro. Although ... Cited by 14 - Related articles - All 8 versions
H Zulewski - Swiss Medical Weekly, 2006 - smw.ch Replacement of insulin-producing cells repre- sents an almost ideal treatment for patients with
diabetes mellitus type 1. Transplantation of pan- creatic islets of Langerhans – although
successful in experienced centres ... Cited by 11 - Related articles - View as HTML - BL Direct - All 5 versions
- ►cell.com MV Joglekar, VS Parekh, AA Hardikar - Trends in Endocrinology & Metabolism, 2007 - Elsevier MicroRNAs (miRNAs) are 18–22 nucleotide RNA molecules that mediate post-transcriptional gene
silencing, primarily by binding to the 3′ untranslated region of their target mRNA. Several
studies have demonstrated the role ... Cited by 5 - Related articles - All 4 versions
- ►diabetesjournals.org A Misfeldt… - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In control mice, PPx stimulated β-cell proliferation and neogenesis and upregulated Foxm1
and several of its known targets (Plk1, Cenp-a, Birc5/Survivin, and Ccnb1) in islets. Within 1 week
post-PPx, control mice underwent ... Cited by 4 - Related articles - All 3 versions
