- ►pnas.org RH Lee, MJ Seo, RL Reger, JL Spees, AA … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences We tested the hypothesis that multipotent stromal cells from human bone marrow
(hMSCs) can provide a potential therapy for human diabetes mellitus. Severe but
nonlethal hyperglycemia was produced in NOD/scid mice with daily low doses ... Cited by 105 - Related articles - BL Direct - All 14 versions
- ►alphamedpress.org O Karnieli, Y Izhar-Prato, S Bulvik, S Efrat - Stem Cells, 2007 - AlphaMed Press We have recently shown that stable expression of pancreatic duodenal homeobox 1
(PDX1), a transcription factor that plays key roles in pancreas development and
β-cell gene expression, in cultured human fetal liver cells activates a ... Cited by 44 - Related articles - BL Direct - All 6 versions
- ►cell.com ST Gangaram-Panday, MM Faas, P de Vos - Trends in Molecular Medicine, 2007 - Elsevier Many approaches of stem-cell therapy for the treatment of diabetes have been
described. One is the application of stem cells for replacement of nonfunctional
islet cells in the native endogenous pancreas; another one is the use of ... Cited by 30 - Related articles - All 6 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative
lack of insulin-producing β cells, respectively. Reconstitution of a functional
β-cell mass by cell therapy – using organ donor islets of Langerhans – ... Cited by 27 - Related articles - BL Direct - All 6 versions
- ►endojournals.org Y Hasegawa, T Ogihara, T Yamada, Y Ishigaki, … - Endocrinology, 2007 - Endocrine Soc There is controversy regarding the roles of bone marrow (BM)-derived cells in
pancreatic ß-cell regeneration. To examine these roles in vivo, mice were
treated with streptozotocin (STZ), followed by bone marrow transplantation ... Cited by 27 - Related articles - BL Direct - All 4 versions
SUN Yu, C Li, HOU Xin-guo, HOU Wei-kai, D … - Chinese medical journal, 2007 - cmj.org Bckground Stem cells, which have the ability to differentiate into
insulin-producing cells (IPCs), would provide a potentially unlimited source of
islet cells for transplantation and alleviate the major limitations of ... Cited by 25 - Related articles - Cached - BL Direct - All 8 versions
- ►shouxi.net AE Butler, A Huang, PN Rao, A Bhushan, WJ … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Type 1 and type 2 diabetes are characterized by an ∼98 and ∼65%
loss of pancreatic β-cells, respectively. Efforts to reverse either form of
diabetes increasingly focus on the possibility of promoting β-cell ... Cited by 17 - Related articles - BL Direct - All 6 versions
CM Chang, CL Kao, YL Chang, MJ Yang, YC … - Biochemical and Biophysical Research …, 2007 - Elsevier In the present study, we successfully isolated PDMSCs from human placental
tissues. The RT-PCR results show that PDMSCs preserved the genetic
characteristics of the primitive embryonic stage—Oct-4 and Nanog. By ... Cited by 15 - Related articles - All 5 versions
TG Fellous, NJ Guppy, M Brittan, MR Alison - Diabetes/Metabolism Reviews - interscience.wiley.com In the twenty-first century, diabetic patients are likely to be one of the major
beneficiaries from the advancement of regenerative medicine through cellular
therapies. Though the existence of a specific self-renewing stem cell ... Cited by 15 - Related articles - BL Direct - All 4 versions
M Liu, ZC Han - J Cell Mol Med, 2008 - interscience.wiley.com Mesenchymal stem cells (MSCs) can be derived from adult bone marrow, fat and
several foetal tissues. In vitro, MSCs have the capacity to differentiate into
multiple mesodermal and non-mesodermal cell lineages. Besides, MSCs possess ... Cited by 13 - Related articles - All 3 versions
