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Scholar Results 1 - 10 of about 21 citing Wierup: CART regulates islet hormone secretion and is expressed in the β-cells of type 2.... (0.08 sec) 

CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta …


N Wierup, WG Richards, AW Bannon, MJ Kuhar … - Regulatory peptides, 2005 - Elsevier
CART peptides are anorexigenic and are widely expressed in the central and
peripheral nervous systems, as well as in endocrine cells in the pituitary,
adrenal medulla and the pancreatic islets. To study the role of CART in ...
Cited by 37 - Related articles - All 4 versions

The CART (cocaine-and amphetamine-regulated transcript) system in appetite and drug …

- aspetjournals.org
A Vicentic, DC Jones - Journal of Pharmacology and Experimental …, 2007 - ASPET
CART (cocaine- and amphetamine-regulated transcript) peptides are
neuromodulators that are involved in feeding, drug reward, stress,
cardiovascular function, and bone remodeling. CART peptides are abundant ...
Cited by 25 - Related articles - All 4 versions

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with …

- 171.66.122.45
MP Keller, YJ Choi, P Wang, D Belt Davis, ME … - Genome Research, 2008 - 171.66.122.45
Insulin resistance is necessary but not sufficient for the development of type 2
diabetes. Diabetes results when pancreatic beta-cells fail to compensate for
insulin resistance by increasing insulin production through an expansion of ...
Cited by 27 - Related articles - BL Direct - All 15 versions

[PDF] Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired …


V Lyssenko, CL Nagorny, MR Erdos, N Wierup, … - Nat Genet, 2009 - genome.gov
Genome-wide association studies have shown that variation in MTNR1B (melatonin
receptor 1B) is associated with insulin and glucose concentrations. Here we show
that the risk genotype of this SNP predicts future type 2 diabetes (T2D) in ...
Cited by 24 - Related articles - View as HTML - All 8 versions

Neuropeptides and the regulation of islet function

- shouxi.net
B Ahrén, N Wierup, F Sundler - Diabetes, 2006 - Am Diabetes Assoc
The pancreatic islets are richly innervated by autonomic nerves. The islet
parasympathetic nerves emanate from intrapancreatic ganglia, which are
controlled by preganglionic vagal nerves. The islet sympathetic nerves are ...
Cited by 15 - Related articles - BL Direct - All 4 versions

Cocaine-and amphetamine-regulated transcript regulation of follicle-stimulating hormone …

- endojournals.org
A Sen, A Bettegowda, F Jimenez-Krassel, JJ … - Endocrinology, 2007 - Endocrine Soc
Regulation of estradiol production, central to ovarian follicular development
and reproductive function, is mediated by a complex interaction of pituitary
gonadotropins such as FSH with locally produced regulatory molecules. We ...
Cited by 9 - Related articles - BL Direct - All 3 versions

CART is a novel islet regulatory peptide


N Wierup, F Sundler - Peptides, 2006 - Elsevier
CART peptides have emerged as important islet regulators. CART is expressed both
in islet endocrine cells and in parasympathetic and sensory nerves innervating
the islets. In adult rats the intra-islet expression of CART is limited to ...
Cited by 8 - Related articles - All 5 versions

Islet β-cell area and hormone expression are unaltered in Huntington's disease


K Bacos, M Björkqvist, Å Petersén, L Luts … - Histochemistry and Cell Biology, 2008 - Springer
Histochem Cell Biol (2008) 129:623–629 DOI 10.1007/s00418-008-0393-z ...
Islet -cell area and hormone expression are unaltered ... Karl Bacos · Maria
Björkqvist · Åsa Petersén · Lena Luts · Marion LC Maat-Schieman · ...
Cited by 6 - Related articles - BL Direct - All 4 versions

Mitochondrial mechanism of neuroprotection by CART


P Mao, A Ardeshiri, R Jacks, S Yang, PD Hurn … - The European journal of neuroscience, 2007 - pubmedcentral.nih.gov
We previously demonstrated that the neuropeptide cocaine- and
amphetamine-regulated transcript (CART) is protective against focal cerebral
ischemia in vivo and against neuronal cell death in culture induced by ...
Cited by 4 - Related articles - BL Direct - All 5 versions

Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro- …


N Wierup, A Gunnarsdóttir, E Ekblad, F … - BMC neuroscience, 2007 - biomedcentral.com
The peptide CART is widely expressed in central and peripheral neurons, as well
as in endocrine cells. Known peripheral sites of expression include the
gastrointestinal (GI) tract, the pancreas, and the adrenal glands. In ...
Cited by 4 - Related articles - Cached - All 5 versions


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