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Scholar Results 1 - 10 of about 25 citing Coppey: ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy.... (0.11 sec) 

Treatment of Streptozotocin-Induced Diabetic Rats With AVE7688, a Vasopeptidase Inhibitor

- diabetesjournals.org
EP Davidson, TL Kleinschmidt, CL Oltman, … - Diabetes, 2007 - Am Diabetes Assoc
In epineurial arterioles, acetylcholine-mediated vascular relaxation is mediated
by nitric oxide and endothelium-derived hyperpolarizing factor (EDHF), and both
mechanisms are impaired by diabetes. The mediator responsible for the ...
Cited by 11 - Related articles - BL Direct - All 6 versions

Diabetic neuropathy: new strategies for treatment.


T Varkonyi, P Kempler - Diabetes, Obesity & Metabolism, 2008 - pt.wkhealth.com
Current therapeutic possibilities can be divided into two groups: the
pathogenetically oriented and the symptomatic therapy. One of the most important
component of etiology-based treatment is the stabilization of glycemic ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ...
Cited by 11 - Related articles - All 2 versions

Pro-inflammatory mechanisms in diabetic neuropathy: focus on the nuclear factor kappa B …


NE Cameron, MA Cotter - Current Drug Targets, 2008 - ingentaconnect.com
Abstract: Neuropathy is a common complication of diabetes mellitus, which
reduces the quality of life and may be life- threatening. The etiology is
complex and multifactorial: hyperglycemia and dyslipidemia give rise to ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Vascular and neural dysfunction in Zucker diabetic fatty rats: a difficult condition to reverse.


CL Oltman, EP Davidson, LJ Coppey, TL … - Diabetes, obesity & metabolism, 2008 - pt.wkhealth.com
Results: Motor nerve conduction velocity (MNCV), sensory nerve conduction
velocity (SNCV) (70 and 77% of control, respectively), EBF (64% of control), and
vascular relaxation in response to acetylcholine (50% of control) and ...
Cited by 8 - Related articles - All 4 versions

Role of angiotensin II in endothelial dysfunction induced by lipopolysaccharide in mice

- physiology.org
DD Lund, RM Brooks, FM Faraci, DD Heistad - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
Endotoxin [or lipopolysaccharide (LPS)] increases levels of superoxide in blood
vessels and impairs vasomotor function. Angiotensin II plays an important role
in the generation of superoxide in several disease states, including ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Attenuation of vascular/neural dysfunction in Zucker rats treated with enalapril or …


CL Oltman, EP Davidson, LJ Coppey, TL … - Obesity, 2008 - nature.com
Enalapril treatment decreased serum angiotensin-converting enzyme (ACE) activity
and both drugs reduced serum cholesterol levels. In obese Zucker rats at 32
weeks of age superoxide levels were elevated in the aortas and epineurial ...
Cited by 6 - Related articles - All 3 versions

The effect of nimodipine on calcium homeostasis and pain sensitivity in diabetic rats


L Shutov, I Kruglikov, O Gryshchenko, E … - Cellular and molecular neurobiology, 2006 - Springer
Page 1. Cellular and Molecular Neurobiology, Vol. 26, Nos. 7/8,
October/November 2006 ( C 2006) DOI: 10.1007/s10571-006-9107-z The ...
Cited by 5 - Related articles - BL Direct - All 4 versions

An update on non-peptide angiotensin receptor antagonists and related RAAS modulators

- ucl.ac.be [PDF] 
GK Aulakh, RK Sodhi, M Singh - Life sciences, 2007 - Elsevier
The renin–angiotensin–aldosterone-system (RAAS) is an important regulator of
blood pressure and fluid-electrolyte homeostasis. RAAS has been implicated in
pathogenesis of hypertension, congestive heart failure, and chronic renal ...
Cited by 5 - Related articles - All 5 versions

The potential role of angiotensin converting enzyme and vasopeptidase inhibitors in the …


MA Yorek - Current Drug Targets, 2008 - ingentaconnect.com
Abstract: Diabetic neuropathy is a debilitating disorder that occurs in more
than 50 percent of patients with diabetes. Evidence suggests that there are at
least five major pathways involved in the development of diabetic ...
Cited by 4 - Related articles - BL Direct - All 3 versions


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