- ►diabetesjournals.org JM Forbes, MT Coughlan, ME Cooper - Diabetes, 2008 - Am Diabetes Assoc It is postulated that localized tissue oxidative stress is a key component in
the development of diabetic nephropathy. There remains controversy, however, as
to whether this is an early link between hyperglycemia and renal disease or ... Cited by 42 - Related articles - All 3 versions
H Yamamoto, T Watanabe, Y Yamamoto, H … - Current Molecular Medicine, 2007 - ingentaconnect.com 1 Department of Biochemistry & Molecular Vascular Biology, Kanazawa University
Graduate School of Medi- cal Science, Kanazawa, 2 Department of Biochemistry,
Kanazawa Medical University, Ishikawa, Japan Abstract: As is diabetes ... Cited by 18 - Related articles - BL Direct - All 2 versions
S Toyokuni, S Akatsuka - Pathology International, 2007 - interscience.wiley.com Aerobes, including humans, are consistently exposed to oxidative stress by
consuming oxygen. The biological significance of oxidative stress via reactive
oxygen and nitrogen species consists of two stages: reversible redox ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org T Miyata… - Nephrology Dialysis Transplantation, 2006 - ERA-EDTA In pioneering studies, Mogensen [1] and Parving et al. [2] have demonstrated
that anti-hypertensive treatment slowed the decline of renal function in
hypertensive patients with diabetic nephropathy. These observations were ... Cited by 9 - Related articles - BL Direct - All 6 versions
M Osawa, Y Yamamoto, S Munesue, N … - BBA-General Subjects, 2007 - Elsevier Interactions between advanced glycation endproducts (AGE) and the receptor for
AGE (RAGE) have been implicated in the development of diabetic vascular
complications. RAGE has two N-glycosylation sites in and near the ... Cited by 7 - Related articles - All 2 versions
R Inagi - Recent Patents on Cardiovascular Drug Discovery, 2006 - ingentaconnect.com Received: February 6, 2006; Accepted: February 20, 2006; Revised: February 22,
2006 Abstract: Oxidative stress is a common denominator in many aspects of the
pathogenesis of atherosclerosis and cardio- vascular diseases. Some drugs, ... Cited by 5 - Related articles - All 2 versions
T Miyata, Y Izuhara - Annals of the New York Academy of Sciences, 2008 - ingentaconnect.com Several factors have been incriminated in the genesis of diabetic nephropathy.
To elucidate their interplay, we have used a hypertensive, obese, diabetic rat
model with nephropathy (SHR/NDmcr-cp) that mimics human type 2 diabetes. ... Cited by 3 - Related articles - BL Direct - All 4 versions
KC Sourris, JM Forbes - Current Drug Targets, 2009 - ingentaconnect.com Abstract: Diabetes, is a metabolic disorder characterised by chronic
hyperglycaemia, hypertension, dyslipidaemia, micro- albuminuria and
inflammation. Moreover, there are a number of complications associated with ... Cited by 3 - Related articles - All 2 versions
S Ohtomo, M Nangaku, Y Izuhara, N Yamada, T …, 2008 - nature.com In diabetic nephropathy decreased activities of matrix metalloproteinase
(MMP)-2, MMP-9 and plasmin contribute to mesangial matrix accumulation. Megsin,
a novel member of the serine protease inhibitor superfamily, is ... Cited by 2 - Related articles - All 5 versions
R Thuillier, JP Tillement, T Hauet - Current pharmaceutical design, 2009 - ingentaconnect.com Abstract: Coronary artery disease (CAD) is due to subintimal deposition of
atheromatous plaques in large and medium- sized coronary arteries. Different
risk factors have been identified such as hypertension, ... Cited by 2 - Related articles - All 3 versions
