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Scholar Results 1 - 10 of about 49 citing Kang: Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing. (0.11 sec) 

The AMP-activated protein kinase


DG Hardie, D Carling - European Journal of Biochemistry, 1997 - journal.shouxi.net
The LKB1AMPK cascade is switched on by metabolic stresses that either inhibit ATP production
(eg hypoxia, hypoglycaemia) or that accelerate ATP consumption (eg muscle contraction). Any
decline in cellular energy status is accompanied by a rise in the cellular AMP: ATP ratio, ...
Cited by 719 - Related articles - Cached - BL Direct - All 6 versions

AMP-activated protein kinase–development of the energy sensor concept


DG Hardie, SA Hawley, JW Scott - The Journal of physiology, 2006 - Physiological Soc
The LKB1→AMPK cascade is switched on by metabolic stresses that either inhibit ATP production
(eg hypoxia, hypoglycaemia) or that accelerate ATP consumption (eg muscle contraction). Any
decline in cellular energy status is accompanied by a rise in the cellular AMP: ATP ratio, ...
Cited by 220 - Related articles - BL Direct - All 8 versions

AMPK is essential for energy homeostasis regulation and glucose sensing by …

- nih.gov
M Claret, MA Smith, RL Batterham, C … - Journal of Clinical …, 2007 - Am Soc Clin Investig
1 Centre for Diabetes and Endocrinology, Rayne Institute, University College London,
London, United Kingdom. 2 Neurosciences Institute, Pathology and Neuroscience Division, Ninewells
Hospital and Medical School, University of Dundee, Dundee, United Kingdom. 3 Cellular ...
Cited by 64 - Related articles - BL Direct - All 15 versions

Metabolic sensing neurons and the control of energy homeostasis


BE Levin - Physiology & behavior, 2006 - Elsevier
The brain and periphery carry on a constant conversation; the periphery informs the brain about
its metabolic needs and the brain provides for these needs through its control of
somatomotor, autonomic and neurohumoral pathways involved in energy intake, ...
Cited by 25 - Related articles - All 4 versions

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y …


PD Mountjoy, SJ Bailey, GA Rutter - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Changes in the activity of glucose-excited and glucose-inhibited neurons
within the basomedial hypothalamus are key to the central regulation of satiety. However, the
molecular mechanisms through which these cells respond to extracellular stimuli remain ...
Cited by 25 - Related articles - BL Direct - All 6 versions

Brain glucose sensing, counterregulation, and energy homeostasis.


N Marty, M Dallaporta, B Thorens - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov
Neuronal circuits in the central nervous system play a critical role in orchestrating the control
of glucose and energy homeostasis. Glucose, beside being a nutrient, is also a signal detected
by several glucose-sensing units that are located at different anatomical sites and ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Brain glucose sensing: a subtle mechanism


L Pénicaud, C Leloup, X Fioramonti, A … - Current Opinion in …, 2006 - journals.lww.com
Purpose of review Brain nutrient sensing allows a fine regulation of different physiological
functions, such as food intake and blood glucose, related to energy homeostasis. Glucose sensing
is the most studied function and a parallel has been made between the cellular ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Gonadotropin-releasing hormone neurons express Katp channels that are …

- cjb.net
C Zhang, MA Bosch, JE Levine, OK Ronnekleiv, … - Journal of …, 2007 - neuro.cjb.net
Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that is dependent
on circulating 17ß-estradiol (E2) and glucose concentrations. However, the intrinsic conductances
responsible for the episodic firing pattern underlying pulsatile release and the effects of ...
Cited by 16 - Related articles - All 4 versions

Mechanisms of sympathoadrenal failure and hypoglycemia in diabetes

- nih.gov [PDF] 
PE Cryer - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
A reduced sympathoadrenal response, induced by recent antecedent hypoglycemia, is the key
feature of hypoglycemia-associated autonomic failure (HAAF) and, thus, the pathogenesis of
iatrogenic hypoglycemia in diabetes. Understanding of the mechanism(s) of that reduced ...
Cited by 18 - Related articles - BL Direct - All 11 versions

Role of neuronal glucosensing in the regulation of energy homeostasis

- diabetesjournals.org
BE Levin, L Kang, NM Sanders, AA Dunn-Meynell - Diabetes, 2006 - Am Diabetes Assoc
Glucosensing is a property of specialized neurons in the brain that regulate their membrane
potential and firing rate as a function of ambient glucose levels. These neurons have several
similarities to β- and α-cells in the pancreas, which are also responsive to ambient ...
Cited by 17 - Related articles - BL Direct - All 4 versions


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