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Scholar Results 1 - 10 of about 14 citing Jeon: MCH−/− mice are resistant to aging-associated increases in body weight and insulin.... (0.11 sec) 

Expanding the scales: the multiple roles of MCH in regulating energy balance and other …


P Pissios, RL Bradley, E Maratos-Flier - Endocrine reviews, 2006 - Endocrine Soc
Melanin-concentrating hormone (MCH) is a cyclic peptide originally identified as
a 17-amino-acid circulating hormone in teleost fish, where it is secreted by the
pituitary in response to stress and environmental stimuli. In fish, MCH ...
Cited by 42 - Related articles - BL Direct - All 4 versions

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and …


D Osei-Hyiaman, J Liu, L Zhou, G Godlewski, … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov
Diet-induced obesity is associated with fatty liver, insulin resistance, leptin
resistance, and changes in plasma lipid profile. Endocannabinoids have been
implicated in the development of these associated phenotypes, because mice ...
Cited by 30 - Related articles - All 8 versions

A high-fat, ketogenic diet induces a unique metabolic state in mice

- physiology.org
AR Kennedy, P Pissios, H Otu, B Xue, K … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Ketogenic diets have been used as an approach to weight loss on the basis of the
theoretical advantage of a low-carbohydrate, high-fat diet. To evaluate the
physiological and metabolic effects of such diets on weight we studied mice ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Melanin concentrating hormone is a novel regulator of islet function and growth

- shouxi.net
P Pissios, U Ozcan, E Kokkotou, T Okada, CW … - Diabetes, 2007 - Am Diabetes Assoc
Melanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play
a critical role in energy balance. We have previously reported that
overexpression of MCH is associated with mild obesity. In addition, mice ...
Cited by 14 - Related articles - BL Direct - All 6 versions

Diet, obesity and diabetes: a current update


C Walker, M Zariwala, M Holness - Clinical Science, 2007 - submit.clinsci.org
Abbreviations: ACC, acetyl-CoA carboxylase; AgRP, agouti-related peptide; AMPK,
AMP-activated protein kinase; AQP, aquaglyceroporin; Apo, apolipoprotein; ARC,
arcuate nucleus; BMI, body mass index; CART, cocaine- and ...
Cited by 13 - Related articles - Cached - BL Direct - All 10 versions

Inactivation of the Fto gene protects from obesity


J Fischer, L Koch, C Emmerling, J Vierkotten, T … - Nature, 2009 - nature.com
Several independent, genome-wide association studies have identified a strong
correlation between body mass index and polymorphisms in the human FTO gene 1,
2, 3, 4 . Common variants in the first intron define a risk allele ...
Cited by 15 - Related articles - All 4 versions

Fatty acids increase the circulating levels of oxidative stress factors in mice with diet- …


M Yamato, T Shiba, M Yoshida, T Ide, N Seri, … - FEBS journal, 2007 - interscience.wiley.com
Plasma concentrations of free fatty acids are increased in metabolic syndrome,
and the increased fatty acids may cause cellular damage via the induction of
oxidative stress. The present study was designed to determine whether the ...
Cited by 6 - Related articles - BL Direct - All 4 versions

The orexigenic effect of melanin-concentrating hormone (MCH) is influenced by sex and …

- nih.gov
J Santollo, LA Eckel - Physiology & behavior, 2008 - Elsevier
Recently, it was shown that the orexigenic effect of melanin-concentrating
hormone (MCH) is attenuated by estradiol treatment in ovariectomized (OVX) rats.
This suggests that female rats may be less responsive than male rats to the ...
Cited by 3 - Related articles - All 5 versions

Preclinical Evaluation of Melanin-Concentrating Hormone Receptor 1 Antagonism for the …


DR Gehlert, K Rasmussen, J Shaw, X Li, P … - Journal of Pharmacology and Experimental …, 2009 - ASPET
The mammalian neuropeptide, melanin-concentrating hormone, interacts with two G
protein-coupled receptors, melanin-concentrating hormone receptor (MCHR) 1 and
MCHR2; however, only MCHR1 is expressed in rats and mice. In the present ...
Cited by 3 - Related articles - All 3 versions

The Role of Melanin-Concentrating Hormone in Energy Homeostasis and Mood Disorders


I Antal-Zimanyi, X Khawaja - Journal of Molecular Neuroscience, 2009 - Springer
Abstract The melanin-concentrating hormone (MCH) is a cyclic peptide exerting
its actions through two G-protein- coupled receptors, MCHR1 and MCHR2. MCH is
impli- cated in the regulation of different physiological functions, ...
Cited by 1 - Related articles - All 2 versions


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