- ►nih.gov [PDF] TA Kinard, G De Vries, A Sherman, LS Satin - Biophysical journal, 1999 - Elsevier Glucose triggers bursting activity in pancreatic islets, which mediates the Ca 2+ uptake that
triggers insulin secretion. Aside from the channel mechanism responsible for bursting, which remains
unsettled, it is not clear whether ... Cited by 58 - Related articles - BL Direct - All 12 versions
A Szollosi, M Nenquin, L Aguilar-Bryan, J Bryan, JC … - Journal of Biological …, 2007 - ASBMB In adult β-cells glucose-induced insulin secretion involves two mechanisms (a) a K ATP
channel-dependent Ca 2+ influx and rise of cytosolic [Ca 2+ ] c and (b) a K ATP channel-independent
amplification of secretion without ... Cited by 20 - Related articles - All 5 versions
- ►nih.gov CS Nunemaker, R Bertram, A Sherman, K Tsaneva- … - Biophysical journal, 2006 - Elsevier Pancreatic islets of Langerhans display complex intracellular calcium changes in response to glucose
that include fast (seconds), slow ( 5 min), and mixed fast/slow oscillations; the slow and mixed
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- ►diabetesjournals.org JC Henquin, D Dufrane, M Nenquin - Diabetes, 2006 - Am Diabetes Assoc Pancreatic islets were isolated from 16 nondiabetic organ donors and, after culture for ∼2 days in
5 mmol/l glucose, were perifused to characterize nutrient-induced insulin secretion in human islets.
Stepwise increases from 0 to 30 ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►jbc.org P Stiernet, Y Guiot, P Gilon, JC Henquin - Journal of Biological Chemistry, 2006 - ASBMB Glucose-induced insulin secretion requires a rise in -cell cytosolic Ca 2+ ([Ca 2+ ] c ) that
triggers exocytosis and a mechanistically unexplained amplification of the action of [Ca 2+ ] c .
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- ►angrylapdog.com MJ De Blasio, M Dodic, AJ … - AJP- …, 2007 - ajpendo.physiology.org.p. … An adverse intrauterine environment increases the risk of developing various adult-onset diseases,
whose nature varies with the timing of exposure. Maternal undernutrition in humans can increase
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FK Knop, T Vilsbøll, PV Højberg, S Larsen, S Madsbad, … - Regulatory Peptides, 2007 - Elsevier The initial (0–20 min) insulin and C-peptide responses were enhanced significantly in both groups
by GLP-1 and GIP, respectively, compared to saline (P < 0.05). In both groups GLP-1 infusion
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- ►nih.gov [PDF] IZ Zubrzycki - Biophysical journal, 2002 - Elsevier Sleeping sickness and Chagas disease are among the most severe diseases in Africa as well as Latin
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TG Deering, T Ogihara, AP Trace, B Maier, RG Mirmira - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Within the pancreas, Set7/9 protein shows striking specificity for islet cells, including
α- and β-cells, as well as occasional cells within ducts. Consistent with these findings, the
Set7/9 gene promoter contained an ... Cited by 7 - Related articles - All 3 versions
