- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ... Cited by 97 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org KKY Cheng, KSL Lam, Y Wang, Y Huang, D … - Diabetes, 2007 - Am Diabetes Assoc Adiponectin protects the vascular system partly through stimulation of
endothelial nitric oxide (NO) production and endothelium-dependent vasodilation.
The current study investigated the role of two recently identified ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►jbc.org Y Wu, P Song, J Xu, M Zhang, MH Zou - Journal of Biological Chemistry, 2007 - ASBMB Elevated levels of free fatty acids contribute to cardiovascular diseases, but
the mechanisms remain poorly understood. The present study was aimed to
determine if free fatty acid inhibits the AMP-activated kinase (AMPK). ... Cited by 37 - Related articles - All 5 versions
- ►ahajournals.org Z Xie, Y Dong, R Scholz, D Neumann, MH … - Circulation, 2008 - Am Heart Assoc Methods and Results— Exposure of human umbilical vein endothelial cells or
bovine aortic endothelial cells to metformin significantly increased AMPK
activity and the phosphorylation of both AMPK at Thr172 and LKB1 at Ser428, ... Cited by 35 - Related articles - All 3 versions
B Musicki, AL Burnett - International journal of impotence research, 2006 - nature.com Erectile dysfunction (ED) is highly prevalent in diabetes mellitus.
Pathophysiological mechanisms underlying diabetes-associated ED are in large
part due to endothelial dysfunction, which functionally refers to the ... Cited by 33 - Related articles - BL Direct - All 5 versions
JW Calvert, S Gundewar, S Jha, JJM Greer, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Clinical studies have reported that metformin reduces cardiovascular
end points of type 2 diabetic subjects by actions that cannot solely be
attributed to glucose-lowering effects. The therapeutic effects of ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►jbc.org C Blume, PM Benz, U Walter, J Ha, BE Kemp, … - Journal of Biological Chemistry, 2007 - ASBMB Vasodilator-stimulated phosphoprotein (VASP) is an actin regulatory protein that
links signaling pathways to remodeling of the cytoskeleton. VASP functions are
modulated by protein kinases, which phosphorylate the sites Ser-157, ... Cited by 22 - Related articles - All 5 versions
M Diamant, ME Tushuizen - Current Diabetes Reports, 2006 - Springer Due to global lifestyle changes, obesity (the main driver of type 2 diabetes
[T2D] and cardiovascular disease [CVD]) is reaching pandemic proportions. The
metabolic syndrome, which is regarded as a prediabetic state, is ... Cited by 19 - Related articles - BL Direct - All 2 versions
- ►nih.gov HC Choi, P Song, Z Xie, Y Wu, J Xu, M Zhang … - Journal of Biological Chemistry, 2008 - ASBMB The AMP-activated protein kinase (AMPK) is reported to mediate the beneficial
effects of statin on the vascular functions, but the biochemical mechanisms are
incompletely understood. The aim of the study was to determine how statin ... Cited by 18 - Related articles - All 5 versions
