S Cauchi, D Meyre, C Dina, H Choquet, C … - Diabetes, 2006 - Am Diabetes Assoc Recently, the transcription factor 7-like 2 (TCF7L2) gene has been associated
with type 2 diabetes in subjects of European origin in the DeCode study. We
genotyped the two most associated variants (rs7903146 and rs12255372) in ... Cited by 150 - Related articles - BL Direct - All 3 versions
- ►biologists.org LC Murtaugh - Development, 2007 - dev.biologists.org The development of insulin-producing pancreatic beta (ß)-cells represents the
culmination of a complex developmental program. Cells of the posterior foregut
assume a pancreatic identity, cells within the expanding pancreatic ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►endojournals.org MC Jorgensen, J Ahnfelt-Ronne, J Hald, OD … - Endocrine Reviews, 2007 - Endocrine Soc Pancreas morphogenesis and cell differentiation are highly conserved among
vertebrates during fetal development. The pancreas develops through simple
budlike structures on the primitive gut tube to a highly branched organ ... Cited by 37 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org M Attali, V Stetsyuk, A Basmaciogullari, V … - Diabetes, 2007 - Am Diabetes Assoc The importance of mesenchymal-epithelial interactions for normal development of
the pancreas was recognized in the early 1960s, and mesenchymal signals have
been shown to control the proliferation of early pancreatic progenitor ... Cited by 14 - Related articles - BL Direct - All 5 versions
G Guillemain, G Filhoulaud, G Da Silva- … - Journal of Biological Chemistry, 2007 - ASBMB Mature pancreatic cells develop during embryonic life from endodermal
progenitors, and this developmental process depends on activation of a hierarchy
of transcription factors. While information is available on mesodermal ... Cited by 5 - Related articles - All 6 versions
S Zertal-Zidani, A Bounacer, R Scharfmann - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Epithelium–mesenchyme interactions play a major role
in pancreas development. Recently, we demonstrated that embryonic pancreatic
mesenchyme en- hanced progenitor cell proliferation but inhibited endocrine ... Cited by 5 - Related articles - BL Direct - All 4 versions
- ►nih.gov S Wang, J Hecksher-Sorensen, Y Xu, A Zhao, … - Developmental biology, 2008 - Elsevier High levels of Ngn3 expression in pancreatic progenitor cells are both necessary
and sufficient to initiate endocrine differentiation. While it is clear that the
Notch-Hes1-mediated signals control the number of Ngn3-expressing cells in ... Cited by 6 - Related articles - All 5 versions
- ►nih.gov C Haumaitre, O Lenoir, R Scharfmann - Molecular and Cellular Biology, 2008 - Am Soc Microbiol During pancreas development, transcription factors play critical roles in
exocrine and endocrine differentiation. Transcriptional regulation in eukaryotes
occurs within chromatin and is influenced by posttranslational histone ... Cited by 6 - Related articles - All 4 versions
A Villasenor, DC Chong, O Cleaver - Developmental Dynamics, 2008 - interscience.wiley.com Ngn3 is a bHLH transcription factor critical for the specification of endocrine
cells in the pancreatic Islets of Langerhans. Previous studies in mouse embryos
have reported transient expression of Ngn3 in scattered cells within the ... Cited by 2 - Related articles - All 3 versions
B Duvillie, M Heinis, V Stetsyuk - Development of the Pancreas and Neonatal Diabetes: …, 2007 - books.google.com Shield JPH, Scharfmann R (eds): Development of the Pancreas and Neonatal
Diabetes. Endocr Dev. Basel, Karger, 2007, vol 12, pp 46-54 In vivo and in vitro
Techniques to Study Pancreas Development and Islet Cell Function Bertrand ... Cited by 1 - Related articles - BL Direct - All 4 versions
