- ►cam.ac.uk [PDF] B Borgonovo, J Ouwendijk, M Solimena - Current opinion in cell biology, 2006 - Elsevier Since their discovery by electron microscopy more than fifty years ago,
secretory granules (SGs, also known as large dense core vesicles) of
neuroendocrine cells have attracted the attention of cell biologists. This ... Cited by 17 - Related articles - All 5 versions
- ►shouxi.net RN Bergman - Diabetes, 2007 - Am Diabetes Assoc Type 2 diabetes is increasing at alarming rates in the US, in Westernized
countries, and in the third world. The increasing costs in terms of human
suffering as well as economics are well recognized (1). Improved ... Cited by 16 - Related articles - BL Direct - All 9 versions
PE MacDonald, P Rorsman - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov Exocytosis of insulin-containing secretory vesicles in pancreatic beta-cells is
crucial to maintenance of plasma glucose levels. They fuse with the plasma
membrane in a regulated manner to release their contents and are ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►cell.com DJ Michael, H Cai, W Xiong, J Ouyang, RH … - Trends in Endocrinology & Metabolism, 2006 - Elsevier According to the classical view, peptide hormones are stored in large dense-core
vesicles that release all of their cargo rapidly and completely when they fuse
with and flatten into the plasma membrane. However, recent imaging studies ... Cited by 13 - Related articles - All 4 versions
H Kasai, T Kishimoto, T Nemoto, H … - Advanced drug delivery reviews, 2006 - Elsevier Two-photon excitation imaging is the least invasive optical approach to study
living tissues. We have established two-photon extracellular polar-tracer (TEP)
imaging with which it is possible to visualize and quantify all exocytic ... Cited by 12 - Related articles - All 5 versions
- ►diabetesjournals.org DJ Michael, W Xiong, X Geng, P Drain, RH … - Diabetes, 2007 - Am Diabetes Assoc In healthy individuals, plasma insulin levels oscillate in both fasting and fed
states. Numerous studies of isolated pancreata and pancreatic islets support the
hypothesis that insulin oscillations arise because the underlying rate of ... Cited by 8 - Related articles - BL Direct - All 5 versions
A Schulte, W Schuhmann - ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN …, 2007 - interscience.wiley.com Needle-type voltammetric ultramicroelectrodes show exceptional sensitivity for
the detection of redox-active substances, rapid response times, and total tip
diameters in the lower micrometer range. These characteristics make them ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►nih.gov Y Chen, S Wang, A Sherman - Biophysical Journal, 2008 - Elsevier A kinetic model for insulin secretion in pancreatic β-cells is adapted from a
model for fast exocytosis in chromaffin cells. The fusion of primed granules
with the plasma membrane is assumed to occur only in the “microdomain” ... Cited by 3 - Related articles - All 5 versions
- ►solvingdiabetes.org [PDF] RN Bergman - Diabetes, 2007 - Am Diabetes Assoc T ype 2 diabetes is increasing at alarming rates in the US, in Westernized
countries, and in the third world. The increasing costs in terms of human
suffering as well as economics are well recognized (1). Improved ... Cited by 2 - Related articles - All 2 versions
T Giordano, C Brigatti, P Podini, E Bonifacio, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis We investigated, in three beta cell lines (INS-1E,
RIN-5AH, betaTC3) and in human and rodent primary beta cells, the storage and
release of chromogranin B, a secretory protein expressed in beta cells and ... Cited by 2 - Related articles - BL Direct - All 2 versions