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Scholar Results 1 - 10 of about 39 citing Naruse: Activation of vascular protein kinase C-β inhibits Akt-dependent endothelial nitric.... (0.15 sec) 

Cardiovascular actions of insulin

- endojournals.org
R Muniyappa, M Montagnani, KK Koh, MJ Quon - Endocrine reviews, 2007 - Endocrine Soc
Insulin has important vascular actions to stimulate production of nitric oxide from
endothelium. This leads to capillary recruitment, vasodilation, increased blood flow, and subsequent
augmentation of glucose disposal in classical insulin target tissues (e.g., skeletal muscle). ...
Cited by 101 - Related articles - BL Direct - All 5 versions

The role of protein kinase C activation and the vascular complications of diabetes


N Das Evcimen, GL King - Pharmacological research, 2007 - Elsevier
Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in production
of insulin by the pancreas, and by resistance to insulin's effects. Such a deficiency results in increased
concentrations of glucose and other metabolites in the blood, which in turn damages ...
Cited by 64 - Related articles - All 4 versions

Restoration of coronary endothelial function in obese Zucker rats by a low- …

- physiology.org
M Focardi, GM Dick, A Picchi, C Zhang, … - American Journal of …, 2007 - Am Physiological Soc
A popular diet used for weight reduction is the low-carbohydrate diet, which has most calories
derived from fat and protein, but effects of this dietary regimen on coronary vascular function
have not been identified. We tested the hypothesis that obesity-induced impairment in ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & …, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes, affecting 50% of
diabetic patients. Currently, the only treatment for diabetic neuropathy is glucose control and
careful foot care. In this review, we discuss the idea that excess glucose overloads the ...
Cited by 11 - Related articles - All 2 versions

17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide …

- aspetjournals.org
A Miyazaki-Akita, T Hayashi, QF Ding, H Shiraishi, T … - Journal of Pharmacology …, 2007 - ASPET
In postmenopausal women, the risk of diabetic cardiovascular disease drastically increases compared
with that of men or premenopausal women. However, the mechanism of this phenomenon has
not yet been clarified. We hypothesized that the beneficial effects of estrogen on ...
Cited by 9 - Related articles - All 5 versions

Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction

- ahajournals.org
A Kawakami, M Osaka, M Tani, H Azuma, FM Sacks, K … - Circulation, 2008 - Am Heart Assoc
Methods and Results— ApoCIII inhibited insulin-induced tyrosine phosphorylation of insulin
receptor substrate 1 (IRS-1), decreasing phosphatidylinositol 3-kinase (PI3K)/Akt activation in
human umbilical vein endothelial cells. These effects of apoCIII led to reduced ...
Cited by 8 - Related articles - All 6 versions

Kinase inhibitors for cardiovascular disease


R Kumar, VP Singh, KM Baker - Journal of molecular and cellular cardiology, 2007 - Elsevier
Over the last decade, there has been substantial progress toward understanding the pathophysiology
and treatment of cardiovascular diseases (CVDs). Elucidating cellular responses to the extracellular
environment and signal transduction mechanisms have provided the opportunity to ...
Cited by 7 - Related articles - All 17 versions

Differential Regulation of VEGF Signaling by PKC-{alpha} and PKC-{epsilon} in …

- ahajournals.org
C Rask-Madsen, GL King - Arteriosclerosis, Thrombosis, and Vascular …, 2008 - Am Heart Assoc
Methods and Results— Transfection of bovine aortic endothelial cells with small interfering RNA
(siRNA) targeting either PKC- , , or caused a reduction in the cognate PKC protein by 76% to
89% without changing expression of nontargeted isoforms. Downregulation of PKC- ...
Cited by 8 - Related articles - All 5 versions

Cigarette smoke-induced alterations in endothelial nitric oxide synthase …


L Wagner, B Laczy, M Tamaskó, I Mazák, L Markó, … - Endothelium, 2007 - informahealthcare.com
Endothelial nitric oxide synthase (eNOS) is regulated by phosphorylation of Ser(1177) and
Thr(495), which affects NO bioavailability. Cigarette smoke disturbs the eNOS-cGMP-NO pathway
and causes decreased NO production. Here the authors investigated the acute effects of ...
Cited by 6 - Related articles - BL Direct - All 4 versions

[PDF] Integration of the metabolic and cardiovascular effects of exercise


AJM Wagenmakers - mailman.cs.bham.ac.uk
Page 1. Page 1 14 Integration of the metabolic and cardiovascular effects of exercise Anton JM
Wagenmakers*,**, Natal AW van Riel**, Michael P Frenneaux***, and Paul M Stewart****
*Exercise Metabolism and Biochemistry Group, School of Sport and Exercise ...
Cited by 6 - Related articles - View as HTML - BL Direct - All 3 versions


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