- ►nih.gov R Boushel, E Gnaiger, P Schjerling, M Skovbro, R … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated with mitochondrial
dysfunction. The aim of the present study was to test the hypothesis that oxidative phosphorylation
and electron transport capacity are dimin- ished in the skeletal muscle of type 2 diabetic ... Cited by 80 - Related articles - BL Direct - All 9 versions
- ►nih.gov S Schenk, JF Horowitz - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Fatty acid oversupply is a key mediator of skeletal muscle insulin resistance in obesity, primarily
via accumulation of fatty acid metabolites and activation of proinflammatory pathways.
Herein, we demonstrate that fatty acid–induced insulin resistance in humans is ... Cited by 48 - Related articles - BL Direct - All 10 versions
SA Harrison, CP Day - British Medical Journal, 2007 - gut.bmj.com Compared with our ancestors, Western societies today lead a lifestyle that is much more
sedentary, probably as a result of cultural changes stemming from modern socio-economic
morays. Taking into account differences in body size, our energy expenditure per ... Cited by 40 - Related articles - BL Direct - All 3 versions
HF Kramer, LJ Goodyear - Journal of Applied Physiology, 2007 - Am Physiological Soc Mitogen-activated protein kinases (MAPKs) and NF- B are two major regulators of gene transcription
and metabolism in response to oxidative, energetic, and mechanical stress in skeletal
muscle. Chronic activation of these signaling pathways has been implicated in the ... Cited by 37 - Related articles - All 6 versions
ER Ropelle, JR Pauli, PO Prada, CT de … - The Journal of …, 2006 - Physiological Soc Lifestyle interventions including exercise programmes are cornerstones in the prevention of
obesity-related diabetes. In this study, we demonstrate that a single bout of exercise inhibits
high-fat diet-induced insulin resistance. Diet-induced obesity (DIO) increased the ... Cited by 35 - Related articles - BL Direct - All 8 versions
NPE Kadoglou, F Iliadis, N Angelopoulou, D … - European Journal of …, 2007 - journals.lww.com Background Diabetes mellitus (DM) and chronic inflammation are strongly related to increased
cardiovascular risk. The purpose of this study was to evaluate whether an aerobic training programme
would ameliorate inflammatory and anti-inflammatory markers in patients with type 2 DM. ... Cited by 27 - Related articles - BL Direct - All 18 versions
M Kaneki, N Shimizu, D Yamada, K … - Antioxidants & Redox …, 2007 - liebertonline.com I NSULIN RESISTANCE is a major causative factor for type 2 diabetes, which is a polygenic disease
accounting for >90% of patients with diabetes, and is associated with in- creased risk of cardiovascular
disease. Obesity is pandemic worldwide. Therefore, the pathogenesis of obesity-related ... Cited by 18 - Related articles - BL Direct - All 5 versions
B Gualano, RB Novaes, GG Artioli, TO Freire, DF … - Amino acids, 2008 - Springer Amino Acids (2008) 34: 245–250 DOI 10.1007/s00726-007-0508-1 Printed in The Netherlands ... Effects of creatine supplementation on glucose tolerance and insulin sensitivity in sedentary
healthy males undergoing aerobic training ... B. Gualano, RB Novaes, GG Artioli, TO ... Cited by 16 - Related articles - BL Direct - All 7 versions
AM Abbatecola, G Paolisso - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: Due to the fact that the percentage of aged subjects in the populations of industrialized
countries is dramatically increasing, the scientific community has been obligated to focus their
attention on age related disease states and peculiar consequences of aging such as, ... Cited by 14 - Related articles - BL Direct - All 3 versions
