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Scholar Results 1 - 10 of about 54 citing Devaraj: Increased monocytic activity and biomarkers of inflammation in patients with type.... (0.08 sec) 

Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies


T Mazzone, A Chait, J Plutzky - The Lancet, 2008 - Elsevier
Individuals with type 2 diabetes mellitus have increased cardiovascular disease
risk compared with those without diabetes. Treatment of the residual risk, other
than blood pressure and LDL-cholesterol control, remains important as the ...
Cited by 37 - Related articles - All 11 versions

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or …

- ahajournals.org
JE Kanter, F Johansson, RC LeBoeuf, KE … - Circulation research, 2007 - Am Heart Assoc
It is becoming increasingly clear that suboptimal blood glucose control results
in adverse effects on large blood vessels, thereby accelerating atherosclerosis
and cardiovascular disease, manifested as myocardial infarction, stroke, ...
Cited by 33 - Related articles - All 8 versions

Hyperglycemia and the pathobiology of diabetic complications


D Aronson - Advances in cardiology, 2008 - content.karger.com
Abstract Both type I and type II diabetes are powerful and independent risk
factors for coronary artery disease (CAD), stroke, and peripheral arterial
disease. Atherosclerosis accounts for virtually 80% of all deaths among ...
Cited by 32 - Related articles - BL Direct - All 3 versions

Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with …

- endojournals.org
S Devaraj, MR Dasu, J Rockwood, W Winter, SC … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
Context: Type 1 diabetes (T1DM) is associated with increased cardiovascular
mortality. It is a pro-inflammatory state as evidenced by increased circulating
biomarkers and monocyte activity. The toll-like receptors (TLRs) are ...
Cited by 21 - Related articles - BL Direct - All 4 versions

High glucose induces IL-1beta expression in human monocytes: mechanistic insights

- physiology.org
MR Dasu, S Devaraj, I Jialal - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Previously, IL-1 secretion from Type 2 diabetic patients has been shown to be
increased compared with controls. In this study, we aimed to delineate the
mechanism of IL-1 induction under high-glucose (HG) conditions in human ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Type 1 diabetes, hyperglycaemia, and the heart


R Retnakaran, B Zinman - The Lancet, 2008 - Elsevier
Type 1 diabetes is associated with a substantially increased risk of
cardiovascular disease that might not always be appreciated in view of the
fairly young age of patients with this condition. In fact, in type 1 ...
Cited by 19 - Related articles - All 9 versions

Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: …

- jimmunol.org
Z Sui, LF Sniderhan, G Schifitto, RP Phipps, … - The Journal of Immunology, 2007 - Am Assoc Immnol
HIV type 1 (HIV-1)-associated dementia (HAD) is believed to occur due to
aberrant activation of monocyte-derived macrophages and brain-resident
microglial cells by viral proteins as well as by the proinflammatory ...
Cited by 15 - Related articles - BL Direct - All 6 versions

Evidence of increased inflammation and microcirculatory abnormalities in patients with type …

- diabetesjournals.org
S Devaraj, AT Cheung, I Jialal, SC Griffen, D … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Type 1 diabetes is associated with increased microvascular
complications and inflammation. The monocyte-macrophage is a pivotal cell in
atherogenesis. There are scanty data on noninvasive measures of ...
Cited by 14 - Related articles - BL Direct - All 5 versions

High glucose induces toll-like receptor expression in human monocytes: mechanism of …

- diabetesjournals.org
MR Dasu, S Devaraj, L Zhao, DH Hwang, I … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Pharmacological inhibition of protein kinase C (PKC) activity and
NADPH oxidase significantly decreased TLR2 and TLR4 mRNA and protein (P < 0.05).
Knocking down both TLR2 and TLR4 in the cells resulted in a 76% (P < 0.05) ...
Cited by 15 - Related articles - All 6 versions

High T-helper-1 cytokines but low T-helper-3 cytokines, inflammatory cytokines and …


K Stechova, K Bohmova, Z Vrabelova, A Sepa, … - Diabetes/Metabolism Reviews - interscience.wiley.com
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Cited by 11 - Related articles - BL Direct - All 3 versions


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