- ►endojournals.org J Jager, T Grémeaux, M Cormont, Y Le Marchand- … - Endocrinology, 2007 - Endocrine Soc Inflammation is associated with obesity and insulin resistance. Proinflammatory cytokines produced
by adipose tissue in obesity could alter insulin signaling and action. Recent studies have shown
a relationship between IL-1ß level and metabolic syndrome or type 2 diabetes. However, ... Cited by 53 - Related articles - BL Direct - All 8 versions
EB Taylor, D An, HF Kramer, H Yu, NL Fujii, KSC … - Journal of Biological …, 2008 - ASBMB The Akt substrate of 160 kDa (AS160) is phosphorylated on Akt substrate (PAS) motifs in response
to insulin and contraction in skeletal muscle, regulating glucose uptake. Here we discovered
a dissociation between AS160 protein expression and apparent AS160 PAS ... Cited by 34 - Related articles - All 6 versions
GD Cartee, JFP Wojtaszewski - Applied Physiology, Nutrition, …, 2007 - article.pubs.nrc-cnrc.gc.ca Abstract: Insulin and exercise, the most important physiological stimuli to increase glucose transport
in skeletal muscle, trigger a redistribution of GLUT4 glucose transporter proteins from the cell
interior to the cell surface, thereby increasing glucose transport capacity. The most distal ... Cited by 26 - Related articles - Cached - BL Direct - All 4 versions
- ►physiology.org JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of …, 2007 - Am Physiological Soc We investigated time- and intensity-dependent effects of exercise on phosphorylation of Akt substrate
of 160 kDa (AS160) in human skeletal muscle. Subjects performed cycle exercise for 90 min
(67% O 2 peak , n = 8), 20 min (80% O 2 peak , n = 11), 2 min (110% of peak work rate, n ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►endojournals.org N Ghosh, N Patel, K Jiang, JE Watson, J Cheng, CE … - Endocrinology, 2007 - Endocrine Soc Elevated TNF levels are associated with insulin resistance, but the molecular mechanisms linking
cytokine signaling to impaired insulin function remain elusive. We previously demonstrated a
role for Akt in insulin regulation of protein kinase CßII alternative splicing through ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►physiology.org H Sharfi, H Eldar-Finkelman - American Journal of Physiology- …, 2008 - Am Physiological Soc Serine phosphorylation of insulin receptor substrate (IRS) proteins is a potential inhibitory mechanism
in insulin signaling. Here we show that IRS-2 is phosphorylated by glycogen synthase kinase
(GSK)-3. Phosphorylation by GSK-3 requires prior phosphorylation of its substrates, ... Cited by 8 - Related articles - BL Direct - All 3 versions
JT Treebak, C Frøsig, C Pehmøller, S Chen, SJ … - Diabetologia, 2009 - Springer Page 1. ARTICLE Potential role of TBC1D4 in enhanced post-exercise insulin action in human
skeletal muscle JT Treebak & C. Frøsig & C. Pehmøller & S. Chen & SJ Maarbjerg & N. Brandt
& C. MacKintosh & JR Zierath & DG Hardie & B. Kiens & EA Richter & H. Pilegaard & ... Cited by 7 - Related articles - All 2 versions
- ►shouxi.net Z Yi, P Langlais, EA De Filippis, M Luo, CR Flynn, S … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Research has focused on insulin receptor substrate (IRS)-1 as a locus for insulin
resistance. Tyrosine phosphorylation of IRS-1 initiates insulin signaling, whereas serine/threonine
phosphorylation alters the ability of IRS-1 to transduce the insulin signal. Of 1,242 amino ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►endojournals.org [PDF] J Jager, T Grémeaux, M Cormont, Y Le Marchand- … - Endocrinology, 2006 - Endocrine Soc Page 1. - 1 - INTERLEUKIN-1β−INDUCED INSULIN RESISTANCE IN ADIPOCYTES THROUGH
DOWN-REGULATION OF IRS-1 EXPRESSION Running Title: IL-1β and insulin resistance Jennifer
Jager, Thierry Grémeaux, Mireille Cormont , Yannick Le Marchand-Brustel, and ... Cited by 6 - Related articles - All 2 versions
AS Deshmukh, JA Hawley, JR Zierath - International Journal of Obesity, 2008 - nature.com Efforts to identify exercise-induced signaling events in skeletal muscle have been influenced
by ground-breaking discoveries in the insulin action field. Initial discoveries demonstrating that
exercise enhances insulin sensitivity raised the possibility that contraction directly ... Cited by 4 - Related articles - All 3 versions
