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Scholar Results 1 - 10 of 11 citing Sun: Haplotype structures and large-scale association testing of the 5′ AMP-activated protein.... (0.09 sec) 

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated …


R Saxena, L Gianniny, NP Burtt, V Lyssenko, C … - Diabetes, 2006 - Am Diabetes Assoc
Recently, common noncoding variants in the TCF7L2 gene were strongly associated with increased
risk of type 2 diabetes in samples from Iceland, Denmark, and the US We genotyped 13 single
nucleotide polymorphisms (SNPs) across TCF7L2 in 8,310 individuals in family-based ...
Cited by 160 - Related articles - BL Direct - All 4 versions

Computational disease gene identification: a concert of methods prioritizes type 2 …

- nih.gov
N Tiffin, E Adie, F Turner, HG Brunner, MA van … - Nucleic acids …, 2006 - Oxford Univ Press
Genome-wide experimental methods to identify disease genes, such as linkage analysis and
association studies, generate increasingly large candidate gene sets for which comprehensive
empirical analysis is impractical. Computational methods employ data from a variety of ...
Cited by 48 - Related articles - BL Direct - All 20 versions

Medical sequencing at the extremes of human body mass

- nih.gov
N Ahituv, N Kavaslar, W Schackwitz, A … - The American Journal of …, 2007 - Elsevier
Body weight is a quantitative trait with significant heritability in humans. To identify potential genetic
contributors to this phenotype, we resequenced the coding exons and splice junctions of 58 genes
in 379 obese and 378 lean individuals. Our 96-Mb survey included 21 genes associated ...
Cited by 41 - Related articles - BL Direct - All 19 versions

AMP-kinase {alpha} 2 subunit gene PRKAA2 variants are associated with total …


NJ Spencer-Jones, D Ge, H Snieder, U Perks, R … - British Medical …, 2006 - jmg.bmj.com
Results: All tSNPs were associated with total- and LDL-cholesterol, (p<0.001 to 0.034), explaining
variances of 0.13–0.59% and 0.11–0.55% respectively. One haplotype (frequency 34.7%) showed
lower total- and LDL-cholesterol compared with the most common haplotype (frequency ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and …


P Weyrich, F Machicao, H Staiger, P Simon, C Thamer, … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Role of AMP-activated protein kinase gamma 3 genetic variability in
glucose and lipid metabolism in non- diabetic whites P. Weyrich & F. Machicao & H. Staiger
& P. Simon & C. Thamer & J. Machann & F. Schick & A. Guirguis & ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Single nucleotide polymorphisms in genes encoding LKB1 (STK11), TORC2 ( …

- tokushima-u.ac.jp [PDF] 
P Keshavarz, H Inoue, N Nakamura, T Yoshikawa, … - Molecular Genetics and …, 2008 - Elsevier
The LKB1–AMPK–TORC2 signaling pathway controls glucose homeostasis in the liver, and
mediates therapeutic effects of insulin-sensitizing antidiabetic agents. To examine whether genetic
variations in genes encoding components of this signaling pathway contribute to ...
Cited by 3 - Related articles - All 3 versions

Association testing of common variants in the insulin receptor substrate-1 gene ( …


JC Florez, M Sjögren, CM Agapakis, NP Burtt, P … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Association testing of common variants in the insulin receptor substrate-1 gene
(IRS1) with type 2 diabetes JC Florez & M. Sjögren & CM Agapakis & NP Burtt & P. Almgren &
U. Lindblad & G. Berglund & T. Tuomi & D. Gaudet & MJ Daly & KG Ardlie & ...
Cited by 3 - Related articles - BL Direct - All 4 versions

AMP-kinase alpha2 subunit gene PRKAA2 variants are associated with total-, LDL- …

- nih.gov
NJ Spencer-Jones, D Ge, H Snieder, U Perks, R … - British Medical …, 2006 - jmg.bmj.com
Online First articles must include the digital object identifier (DOIs) and date of initial
publication. establish publication priority; they are indexed by PubMed from initial
publication. Citations to may be posted when available prior to final publication). Online ...
Cited by 2 - Related articles - All 4 versions

Pharmacogenetics in diabetes


ER Pearson - Current Diabetes Reports, 2009 - Springer
Genetic variation can impact on efficacy and risk of adverse events to commonly used oral agents
in diabetes. Metformin is not metabolized and its mech- anism of action remains debated;
however, several cation transporters have been identified. Variation in these ...
Cited by 1 - Related articles - All 2 versions

Genomic characterization and polymorphism analysis of genes involved in lipid- …


L Lin - deposit.ddb.de
Page 1. Technische Universität München Lehrstuhl für Tierzucht Genomic characterization and
polymorphism analysis of genes involved in lipid- and energy metabolism in swine Li Lin
Vollständiger Abdruck der von der Fakultät Wissenschaftszentrum Weihenstephan für ...
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