T Staeva-Vieira, M Peakman, M Von Herrath - Clinical and Experimental Immunology, 2007 - pubmedcentral.nih.gov Type 1 diabetes (T1D) is often considered the prototype organ-specific
autoimmune disease in clinical immunology circles. The key disease features −
precise destruction of a single endocrine cell type occurring on a distinct ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org T Rydgren, O Vaarala, S Sandler - Journal of Pharmacology and Experimental …, 2007 - ASPET Statins are drugs well known for their cholesterol-lowering properties. Lately,
statins have been shown to possess anti-inflammatory properties that might be
attributed to inhibition of leukocyte adhesion and migration to sites of ... Cited by 6 - Related articles - All 4 versions
- ►bentham.org [PDF] R Ghittoni, E Lazzerini, L Pasini, CT Baldari - Inflammation &# 38; Allergy-Drug Targets (Formerly …, 2007 - ingentaconnect.com Abstract: Statins are cholesterol-lowering drugs extensively used for primary
and secondary prevention of cardiovascular events related to
hypercholesterolemia. Because of their capacity to inhibit HMG-CoA ... Cited by 6 - Related articles - BL Direct - All 5 versions
MS Weber, O Stuve, O Neuhaus, H Hartung, … - International MS Journal, 2007 - msforum.net Introduction Statins are oral inhibitors of the 3-hydroxy-3- methylglutaryl
coenzyme A (HMG-CoA) reductase which are widely prescribed to lower cholesterol.
The enzyme HMG-CoA reductase catalyzes the conversion of HMG-CoA to ... Cited by 3 - Related articles - View as HTML - BL Direct - All 2 versions
C Ulivieri, D Fanigliulo, D Benati, FL Pasini, … - European Journal of Immunology, 2008 - interscience.wiley.com Statins block the activity of HMG-CoA reductase, which catalyses the production
of mevalonate, an intermediate in cholesterol biosynthesis, which is also a
precursor of isoprenoids. In addition to lowering circulating cholesterol, ... Cited by 1 - Related articles - All 3 versions
N Ashman, A Banerjee, MM Yaqoob - Nephron Clinical Practice, 2009 - content.karger.com It has recently been proposed that statins act as vitamin D analogs in binding
the ubiquitously expressed vitamin D receptor, accounting for the perceived
pleiotropic effects of statins (a reduction in cancer risk, prevention of ... Cited by 1 - Related articles - All 4 versions
B Lozanoska-Ochser, M Peakman - Clinical &# 38; Experimental Immunology, 2009 - ingentaconnect.com An important prerequisite for development of insulitis and β-cell destruction
in type 1 diabetes is successful transmigration of autoreactive T cells across
the islet endothelium. Previous work suggests that antigen presentation to ... Related articles - All 2 versions
SC Chow - Archivum Immunologiae et Therapiae Experimentalis, 2009 - Springer Statins are inhibitors of the enzyme 3-hydroxy-3methylglutaryl coenzyme A
(HMG-CoA) and they are the most effective agents for lowering cholesterol in
clinical practice for the treatment of cardiovascular diseases. However, it ... Related articles - All 2 versions
TF Hiemstra - The Lancet, 2006 - Elsevier David Grimes (July 1, p 83) 1 proposes that statins exert their pleiotropic
effects by stimulating the vitamin D endocrine system. This would require
interaction with the vitamin D system in one of two ways: first, statins ... Related articles - All 7 versions
B Lozanoska-Ochser, M Peakman, MD PhD, S … - interscience.wiley.com An important prerequisite for development of insulitis and β-cell destruction
in Type 1 diabetes is successful transmigration of autoreactive T-cells across
the islet endothelium. Previous work suggests that antigen presentation to ... Related articles
