SM Kang, Q Tang, JA Bluestone - Am J Transplant, 2007 - pt.wkhealth.com The involvement of CD4 + CD25 + regulatory T cells (Treg) in general immune homeostasis
and protection from autoimmune syndromes is now well established. Similarly, there has been
increasing evidence for Treg involvement in allograft rejection and current ... Cited by 61 - Related articles - BL Direct - All 5 versions
- ►cell.com D Kabelitz, EK Geissler, B Soria, IS Schroeder, F … - Trends in Immunology, 2008 - Elsevier Type 1 diabetes (T1D) is an autoimmune disease that results from the destruction of insulin-producing
pancreatic islet cells owing to the aggressive effector function of autoreactive T cells. In addition
to lifetime supply of exogenous insulin, whole-pancreas or islet transplantation is ... Cited by 10 - Related articles - All 4 versions
M Battaglia, G Roncarolo… - … &# 38; Allergy-Drug Targets (Formerly …, 2006 - ingentaconnect.com Abstract: In the last two decades, graft survival has been greatly improved by the introduction
of efficient immunosup- pressive drugs. On the other hand, late graft loss caused by chronic rejection
together with the side effects of long-term immunosuppression, remain major obstacles ... Cited by 10 - Related articles - BL Direct - All 2 versions
D Chen, JS Bromberg - American Journal of Transplantation, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 10 - Related articles - BL Direct - All 4 versions
T Lund, B Fosby, O Korsgren, H Scholz, A … - Transplant …, 2008 - interscience.wiley.com Factors that upregulate the inflammatory status of islets probably contribute to detrimental processes
leading to islet loss and impaired post-transplant function. Glucocorticoids have the potential
to counteract inflammation and thus improve islet quality and function. However, ... Cited by 6 - Related articles - All 3 versions
- ►nih.gov D Linfert, T Chowdhry, H Rabb - Transplantation Reviews, 2009 - Elsevier Ischemia reperfusion injury (IRI) is a common and important clinical problem in many different
organ systems, including kidney, brain, heart, liver, lung, and intestine. IRI occurs during all deceased
donor organ transplants. IRI is a highly complex cascade of events that includes ... Cited by 5 - Related articles - All 23 versions
- ►endojournals.org X Huang, DJ Moore, RJ Ketchum, CS Nunemaker, B … - Endocrine …, 2008 - Endocrine Soc Although type 1 diabetes cannot be prevented or reversed, replacement of insulin production
by transplantation of the pancreas or pancreatic islets represents a definitive solution. At
present, transplantation can restore euglycemia, but this restoration is short-lived, ... Cited by 5 - Related articles - All 4 versions
- ►ucsf.edu [PDF] N Zhang, B Schröppel, G Lal, C Jakubzick, X Mao, D … - Immunity, 2009 - Elsevier To determine the site and mechanism of suppression by regulatory T (Treg) cells, we investigated
their migration and function in an islet allograft model. Treg cells first migrated from blood to the
inflamed allograft where they were essential for the suppression of alloimmunity. This ... Cited by 9 - Related articles - All 5 versions
Y Zhao - Expert Rev. Clin. Immunol., 2007 - expert-reviews.com A common goal among current immunosuppressive therapies [1] is to block T-cell activation,
proliferation, function and migration, as well as to deplete T cells. In the last few decades, clinical
graft survival has been greatly improved by the introduction of efficient ... Cited by 1 - Related articles - BL Direct - All 3 versions
D Mineo, J Sageshima, GW Burke, C … - Transplant …, 2009 - interscience.wiley.com For reducing the corticosteroid (CS)-related side-effects, especially cardiovascular events,
CS-sparing protocols have become increasingly common in pancreas transplantation (PT).
Lympho-depleting induction antibodies, such as rabbit anti-thymocyte globulin (rATG) or ... Cited by 1 - Related articles - All 3 versions
