- ►physoc.org P Newsholme, EP Haber, SM Hirabara, ELO … - The Journal of …, 2007 - Physiological Soc It is now widely accepted, given the current weight of experimental evidence, that reactive oxygen
species (ROS) contribute to cell and tissue dysfunction and damage caused by glucolipotoxicity
in diabetes. The source of ROS in the insulin secreting pancreatic β-cells and in the cells ... Cited by 62 - Related articles - BL Direct - All 8 versions
K Maiese, SD Morhan, ZZ Chong - Current neurovascular …, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) affects approximately 170 million individuals worldwide and is expected
to alter the lives of at least 366 million individuals within a future span of 25 years. Of even greater
concern is the premise that these projections are underestimated since they assume ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►endojournals.org LI Rachek, SI Musiyenko, SP LeDoux, GL Wilson - Endocrinology, 2007 - Endocrine Soc A major characteristic of type 2 diabetes mellitus (T2DM) is insulin resistance in skeletal
muscle. A growing body of evidence indicates that oxidative stress that results from increased
production of reactive oxygen species and/or reactive nitrogen species leads to insulin ... Cited by 29 - Related articles - BL Direct - All 4 versions
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) is a significant healthcare concern worldwide that affects more than 165
million individuals leading to cardiovascular disease, nephropathy, retinopathy, and widespread
disease of both the peripheral and central nervous systems. The incidence of ... Cited by 27 - Related articles - BL Direct - All 6 versions
- ►nih.gov K Maiese, F Li, ZZ Chong, YC Shang - Pharmacology and Therapeutics, 2008 - Elsevier No longer considered to be exclusive to cellular developmental pathways, the Wnt family of secreted
cysteine-rich glycosylated proteins has emerged as versatile targets for a variety of conditions
that involve cardiovascular disease, aging, cancer, diabetes, neurodegeneration, and ... Cited by 12 - Related articles - All 4 versions
- ►nih.gov K Maiese - Biomedicine & Pharmacotherapy, 2008 - Elsevier Oxidative stress is a principal pathway for the dysfunction and ultimate destruction of cells in
the neuronal and vascular systems for several disease entities, not promoting the ravages of
oxidative stress to any less of a degree than diabetes mellitus. Diabetes mellitus is ... Cited by 12 - Related articles - All 3 versions
- ►nih.gov K Maiese, ZZ Chong, F Li, YC Shang - Progress in neurobiology, 2008 - Elsevier Given that erythropoietin (EPO) is no longer believed to have exclusive biological activity in the
hematopoietic system, EPO is now considered to have applicability in a variety of nervous system
disorders that can overlap with vascular disease, metabolic impairments, and immune ... Cited by 11 - Related articles - All 4 versions
EMV de Cavanagh, F Inserra, M Ferder, L Ferder - Am J Nephrol, 2007 - content.karger.com Mitochondria are energy-producing organelles that conduct other key cellular tasks. Thus, mitochondrial
damage may impair various aspects of tissue functioning. Mitochondria generate oxygen- and
nitrogen-derived oxidants, being themselves major oxidation targets. Dysfunctional ... Cited by 11 - Related articles - BL Direct - All 4 versions
K Maiese, ZZ Chong, YC Shang, J Hou - Med Res Rev, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 4 - Related articles - All 2 versions
