MC Lawrence, A Jivan, C Shao, L Duan, D Goad, E … - Cell Research, 2008 - nature.com MAP kinases transduce signals that are involved in a multitude of cellular pathways and functions
in response to a variety of ligands and cell stimuli. Aberrant or inappropriate functions of MAPKs
have now been identified in diseases ranging from cancer to inflammatory disease to ... Cited by 18 - Related articles - BL Direct - All 5 versions
F Lechin, B van der Dijs - Neuroendocrinology, 2006 - content.karger.com Raised plasma levels of insulin, glucose and glucagon are found in patients affected by
'hyperinsulinism'. Obesity, hypertension, mammary plus ovary cysts and rheumatic symptoms
are frequently observed in these patients. Sleep disorders and depression are also ... Cited by 10 - Related articles - BL Direct - All 8 versions
M Lawrence, C Shao, L Duan, K McGlynn, MH … - Acta …, 2008 - interscience.wiley.com Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) activities are modulated in a
manner that reflects the secretory demand on β cells to integrate long- and short-term nutrient
sensing information. Our studies have focused on the mechanisms of ERK1/2 activation ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►physiology.org H Cheng, SG Straub, GWG Sharp - American Journal of …, 2007 - Am Physiological Soc Both neurotransmitter release and insulin secretion occur via regulated exocytosis and share
a variety of similar regulatory mechanisms. It has been suggested that Src family tyrosine kinases
inhibit neurotransmitter release from neuronal cells (H. Ohnishi, S. Yamamori, K. Ono, K. ... Cited by 5 - Related articles - BL Direct - All 5 versions
MC Lawrence, K McGlynn, C Shao, L Duan, … - Proceedings of the …, 2008 - nihongo.j-talk.com MAPK pathways regulate transcription through phosphorylation of transcription factors and other
DNA-binding proteins. In pancreatic β -cells, ERK1/2 are required for transcription of the insulin
gene and several other genes in response to glucose. We show that binding of glucose- ... Cited by 2 - Related articles - All 7 versions
A Kowluru - Endocrine reviews, 2009 - Endocrine Soc Glucose-stimulated insulin secretion from the islet -cell involves a sequence of metabolic events
and an in- terplay between a wide range of signaling pathways leading to the generation of second
messengers (e.g., cyclic nucleotides, adenine and guanine nucleotides, soluble lipid ...
FLB van der Dijs - Neuroendocrinology, 2006 - content.karger.com Insulin action at the central nervous system (CNS) plays a primordial role in both glucose and
energy ho- meostasis. Studies first implicated the ventromedial hy- pothalamic area as a key
brain area in energy homeosta- ... Key Words Autoimmune diseases Bed nucleus stria ... Related articles
M Cobb, J Albanesi, T Megraw, YM Chook - edissertations.library.swmed.edu Page 1. THE REGULATION OF CELLULAR LOCALIZATION OF BOTH ACTIVE AND INACTIVE
ERK1/2 APPROVED BY SUPERVISORY COMMITTEE Melanie Cobb, Ph.D. Joseph Albanesi,
Ph.D. Tim Megraw, Ph.D. Yuh-Min Chook, Ph.D. Page 2. DEDICATION ... Related articles
EWMT ter Braak - Diabetes and the Brain, 2009 - books.google.com 10 ter Braak and Stades LONG-TERM COMPLICATIONS T1D may ultimately lead to such dreadful
conditions as blindness, limb amputations, and renal failure calling for dialysis or renal
transplantation. Hence, for both patients and health care workers prevention and delay of ... Related articles
C Broca, J Quoyer, S Costes, N Linck, A Varrault, … - Journal of Biological …, 2009 - ASBMB In pancreatic β-cells, the pituitary adenylate cyclase-activating polypeptide (PACAP) exerts a
potent insulin secretory effect via PAC 1 and VPAC receptors (Rs) through the G s /cAMP/protein
kinase A pathway. Here, we investigated the mechanisms linking PAC 1 R to ERK1/2 ... Related articles - All 3 versions
