R McCrimmon - Diabetic Medicine, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 11 - Related articles - BL Direct - All 3 versions
F Lechin, B van der Dijs - Neuroendocrinology, 2006 - content.karger.com Raised plasma levels of insulin, glucose and glucagon are found in patients affected by
'hyperinsulinism'. Obesity, hypertension, mammary plus ovary cysts and rheumatic symptoms
are frequently observed in these patients. Sleep disorders and depression are also ... Cited by 10 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org RJ McCrimmon, M Shaw, X Fan, H Cheng, Y Ding, MC … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Using gene silencing technology to selectively downregulate
AMPK in the VMH, a key hypothalamic glucose-sensing region, we demonstrate a key role for
AMPK in the detection of hypoglycemia. In vivo hyperinsulinemic-hypoglycemic (50 mg dl ... Cited by 12 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org O Chan, M Lawson, W Zhu, JL Beverly, RS Sherwin - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—To determine whether alterations in counterregulatory responses to hypoglycemia
through the modulation of ATP-sensitive K + channels (K ATP channels) in the ventromedial
hypothalamus (VMH) are mediated by changes in GABAergic inhibitory tone in the VMH, ... Cited by 11 - Related articles - BL Direct - All 5 versions
BE Levin, TC Becker, J Eiki, BB Zhang, AA Dunn- … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The counterregulatory response to insulin-induced hypoglycemia is mediated
by the ventromedial hypothalamus (VMH), which contains specialized glucosensing
neurons, many of which use glucokinase (GK) as the rate-limiting step in glucose's ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►physiology.org L Kang, NM Sanders, AA Dunn-Meynell, … - American Journal of …, 2008 - Am Physiological Soc Antecedent insulin-induced hypoglycemia (IIH) reduces adrenomedullary responses (AMR)
to subsequent bouts of hypoglycemia. The ventromedial hypothalamus [VMH: arcuate (ARC)
+ ventromedial nuclei] contains glucosensing neurons, which are thought to be mediators ... Cited by 6 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org O Chan, H Cheng, R Herzog, D Czyzyk, W Zhu, A … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Quantitative RT-PCR and immunoblots in recurrently hypoglycemic animals revealed
that GAD 65 mRNA and protein were increased 33 and 580%, respectively. Basal VMH GABA
concentrations were more than threefold higher in recurrently hypoglycemic animals. ... Cited by 4 - Related articles - BL Direct - All 4 versions
FLB van der Dijs - Neuroendocrinology, 2006 - content.karger.com Insulin action at the central nervous system (CNS) plays a primordial role in both glucose and
energy ho- meostasis. Studies first implicated the ventromedial hy- pothalamic area as a key
brain area in energy homeosta- ... Key Words Autoimmune diseases Bed nucleus stria ... Related articles
- ►endojournals.org LM Gorton, AM Khan, MA Bohland, G Sanchez-Watts, … - Endocrinology, 2007 - Endocrine Soc The time of day influences the magnitude of ACTH and corticosterone responses to
hypoglycemia. However, little is known about the mechanisms that impart these time-of-day differences
on neuroendocrine CRH neurons in the hypothalamic paraventricular nucleus (PVH). ... Related articles - BL Direct - All 4 versions
SC Haywood, AJ Bree, EC Puente, D … - American Journal of …, 2009 - Am Physiological Soc This study tests the hypothesis that lipids could act as an alternative fuel source in the brain during
insulin-induced hypoglycemia. Male Sprague-Dawley rats were subjected to hyperinsulinemic
(5 mU·kg –1 ·min –1 ) hypoglycemic ( 50 mg/dl) clamps. In protocol 1, intralipid (IL), a fat ... Related articles - All 3 versions
